
Welcome To Vaccine Awareness Network Updated 10 May 2013
Vaccines And How They Are Made The chemicals that go into vaccination - newly updated 13 June 2012
Your Immune System, How It Works And How Vaccines Damage It Vaccines and Immune Dysfunction - updated 28 February 2013
The Herd Immunity Theory - Treating Our Children Like Cattle The Herd Immunity Theory - updated 28 February 2013
Did Vaccines Really Halt Killer Diseases? Did Vaccines Really Stop Diseases? A look at history - updated 10 April 2010 with modern day victim of smallpox vaccine
Vaccination And Abortion The Use Of Foetal Tissue in Vaccines - newly updated 15 March 2012
RU-486 Abortion Killing Pill Abortion Pill That Kills the Mother Too - NEW page!
Vaccines: A Religious Contention Vaccines: A Religious Contention - updated 17 December 2009
Mandating Vaccines Or Not? Mandating Vaccines or Not? My speech to Nuffield Bio Ethics on the pitfalls of mandating vaccination - includes link to vaccinationchoice.org - updated 8 February 2009
Pediacel 5-in-1 Super Jab 5 in 1 vaccine - updated 26 August 2012.
Manufacturer's Information About Pediacel 5-in-1 Vaccine
Autism and Cerebral Palsy From DPT Vaccine Maryamber's Story - and other Cerebral Palsy after Vaccination Cases, updated 13 April 2010
Gardasil and Cervarix - The Cervical Cancer Vaccines Gardasil and Cervarix - The Cervical Cancer Vaccine - now updated 31 March 2010 - Spain Withdraws Batch Of HPV Vaccine
Gardasil Vaccines Continued Gardasil Vaccine Continued And Cases Of Gardasil/Cervarix Damage And Death, updated 10 May 2013
Prevnar Vaccination Prevnar and Pneumonia Vaccinations, including info on PCV 13, updated 3 February 2012
Travel Vaccines Travel Vaccines - updated 14 June 2012
Tetanus Vaccine Tetanus Vaccine - updated 6 May 2012
MMR, Single Vaccines And MMRV Vaccine MMR and Single Measles, Mumps and Rubella vaccines and MMRV information - updated 10 May 2013 - NEW COURT RULING SHOWING MMR CAUSED ASD! Contains Graphic Damage Photo.
Killer Measles Vaccine Is Withdrawn And Other Vaccine Death Cases Four Babies Killed In Measles Vaccine Campaign - updated 26 August 2012 with more deaths, PAGE FULL.
Infant Vaccines Produce Autism Symptoms In Primates Shots Cause Autism In Monkeys
If You Don't Want The MMR We'll Force You and Other Vaccination Force Stories Bully Boy Tactics Proposed - includes case of forced vaccination with various vaccines, updated 10 May 2013
Meningitis C Vaccine Various articles and citations - updated 30 August 2012
Hepatitis B Vaccine...aluminium....thimerosal (mercury)....yeast...but don't worry, it's gluten free! Hep B Manufacturer's Information - updated with details of court admitted MS and Death Caused By Hep B Vaccine, updated 18 November 2012
Hepatitis B Vaccine Kills Baby and other Vaccine Death Cases Updated 10 May 2013
Vaccine Companies Investigated For Manslaughter and other Vaccine Court Cases And Other Vaccine Companies/Doctors On Trial For Vaccine Deaths, Injuries and Fraud - Updated 21 February 2013, now including Investigations into Swine Flu Scam
Iatrogenic Child Abuse Iatrogenic child abuse: vaccinations and other medical abuse of children by doctors
Bullying, Rude and Discriminatory Doctors who Forget Vaccines are a CHOICE Updated 10 May 2013
My Fight For Health After Vaccination A Vaccine Damage Case - updated 6 March 2012 to include my friend's and relatives vaccine damage cases
Vaccine Injury Photos From The CDC WARNING! Very Graphic Vaccine Damage Pictures. Don't Look If Easily Upset - updated 21 August 2011
Vaccine Debate Page A Place Where You Can Send Your Views On Vaccines And Health - updated 21 August 2011
Vaccination And Your Legal Rights Your Legal Right To Own Your Own Body - updated 16 August 2009 with new information
Vaccination DESTROYS Natural Immunity! Transplacental and Breast Milk Immunity and How they are Diminished by Vaccination - new page 10 May 2013
Disease Killing Properties Of Breast Milk Immunising Your Baby With Breast Milk - updated 18 June 2012
Polio: The Disease, the Vaccine and the Controversies NEW Page - updated 26 August 2012
Baby Gallery Unvaccinated Bundles of Joy! - updated 8 May 2013
The Home Birth Pages - My Story The Hospital Birth Experience
The Home Birth Pages My Unassisted Childbirth - Reclaiming My Femininity - updated 17 May 2012
The Home Birth Pages - British Maternity Care (The Bullying I got When Pregnant with Yanny) My Struggle To Have A Natural Pregnancy With The NHS - updated 5 May 2012
The Home Birth Pages - Yanny's Unhindered Home Birth My Baby's Unhindered Home Birth - updated 6 May 2012
Home Birth And Your Legal Rights. How To Have A Natural Birth Your Right To Birth Without Violence And Other Home Birth Issues - updated 17 May 2012
THE DANGERS OF EPISIOTOMY And Tips For Easing Pain. Updated 6 May 2012
Obstetric Myths and Realities Caesareans and Breech Births - updated 17 May 2010
Vaccine Information For Pregnant Women What You Should Know If Considering A Vaccination During Pregnancy - updated 7 October 2012 - ALERT: MISCARRIAGES AND STILLBIRTHS AFTER H1N1 VACCINE!!
Home Education Photo Diary Photo Diary of Child Friendly Home Schooling - updated 7 August 2009 - PAGE FULL, WILL ADD NEW ONE LATER.
Home Education Photo Diary Page two of my children's home schooling - updated 10 February 2013
Home Education And Your Legal Rights Updated 3 March 2012.
Other People's Breast Milk VAN UK'S Founder On 'Other People's Breast Milk' and Comments Regarding The Show
Dangers Of Formula Milk Formula Milk Is NOT As Good As Breast Milk And Is Not A Breast Milk Substitute! Updated 14 June 2012
Vitamin K: Does Your Baby Really Need It? Updated 6 May 2012
Mercury Free Vaccines Still Have Mercury In Them What's Not On The Label
Pro-Vaccine Arguments VS. Medical Evidence - updated 28 February 2013
Pro-Vaccine Arguments Page 2 VS. Medical Evidence - NEW page completed on 25th August 2012
Vaccine Shedding The spreading of viruses and bacteria via vaccination. Includes Information on the symptoms and treatment of measles. Updated 17 July 2012
Why I Don't Vaccinate My Children And The Birth of VAN UK - updated 26 August 2012
Six Reasons Why I Don't Vaccinate My Children Some of the reasons I don't vaccinate, from my blog, 7th October 2012
Vaccines And Sudden Infant Death Syndrome The Link Between Vaccines And SIDS - updated 22 July 2012
Midwives And Health Professionals Against Vaccination Updated 30 August 2012
Media Censorship of Vaccine News Updated 2 June 2012.
Vaccine Victim's Dad Refuses To Bury Him After 21 Years Couragious Dad Refuses To Allow A Definition Of SIDS On His Son's Death Certificate
BCG Vaccine BCG vaccine information - new page 4 August 2012
Homeopathic Vaccination Updated 7 October 2012
Doctor Says Vaccines Cause Micro Vascular Strokes In Babies and Children A conventional doctor links vaccines with strokes, SIDS, Autism and other illnesses - updated 19 October 2010
Boy Partially Losses Hearing After Vaccination Updated 22nd August 2012 with more deafness and blindness after MMR cases
Delaying Vaccination Cuts Asthma Risk (and Other Allergies Related to Vaccines). Citation in the Journal of Allergy And Clinical Immunology and Info on Vaccines and Auto-Immunity - 2 August 2012
Vaccines, Mercury, Aluminium and Autism Studies With link to http://www.mercurymadness.org. Manufacturer's Say Vaccines Cause Autism! - updated 28 February 2013
Contraindications (people who shouldn't be vaccinated) and side-effects From The Merck Manual (vaccine manufacturer) Medical Information On Who Should Not Have Vaccines - Merck and GP Notebook - updated 6 September 2009
Flu Vaccines Updated 28 February 2013
Swine Flu Epidemic/ H1N1 Vaccine Deaths and Injuries Created By Lab Blunder - now recording deaths and injuries from jab - page now full.
Swine Flu Vaccine Ingredients and other information - updated 10 October 2011
Tamiflu What You Should Know About Tamiflu - updated 22 January 2010
More Educated Mothers Are Less Likely To Vaccinate A New Study Shows That University Educated Mums Are More Likely To Refuse Vaccines And Other Studies Showing Educated Mothers Refusing Vaccines - updated 21 February 2013
Diseases In The Vaccinated Medical Studies And Reports Showing Vaccines Do Not Immunise - Updated 25 April 2009
Diseases In The Vaccinated Page 2 Page Full.
Diseases in the Vaccinated - Page 3 Vaccine 'Preventable' Diseases Occuring in the Vaccinated - NEW PAGE. 11 May 2013
Seven School Kids Taken To Hospital After Vaccines and Other Vaccine Disasters Kids sicken after DT/IPV Vaccines - and other reactions after vaccination drives, updated 21 February 2013
Acute disseminated encephalomyelitis after vaccination caused girl to have one and a half hour seizure And other encephalitis after vaccination, updated 17 October 2009
Infant Mortality Rates Fall Where 'Immunisation' Rates Are Low Infant Mortality Rates Fall In Line With Lowering Vaccination Rates - updated 31 January 2013
Chickenpox: Is It Really A Killer Disease? Suddenly this benign childhood illness has turned into a 'deadly killer' because they are introducing a vaccine - updated 31 January 2013
Selective Vaccination If You Decide To Vaccinate - updated 30 January 2013
Vaccine Damage Payments Unit How To Make A Claim For Compensation If Your Loved One Is Vaccine Injured - updated 23 March 2009
Healing From Vaccine Damage A Case Study Using Homeopathy to Detox from Vaccines - page created 6 May 2009.
Legal Help For Vaccine Damage And Pro-Choice Issues Solicitor/Lawyer Information - updated 2 June 2012
Treating Childhood Illnesses These days, doctors and parents have lost the art of actually nursing their child through a normal childhood illness. Here we tell you the symptoms and treatment of measles, mumps, rubella, chickenpox, rotavirus and whooping cough - updated 15 June 2012
Childhood Diseases Can Be Good For Your Child! Studies showing childhood diseases reduce autoimmunity - updated 21 November 2010
Stupid Medical Advice Which Has Been Consigned To History Books Updated 12 April 2012
Double Standards - it's not okay to ingest this but fine if we inject it Authorities Admitting Concern Over Chemicals Used In Other Products That Are Also Used In Vaccines - updated 30 January 2013
Ian's Life A page dedicated to a little boy who died of an adverse reaction to Hepatitis B vaccine. WARNING: graphic vaccine damage picture
Animal Vaccines The Dangers of Animal Vaccines and naturally rearing animals - updated 27 September 2012
Remember My Name Honouring Those Who Have Died From Vaccination - updated 15 April 2012
Remember My Name - Page 2 Honouring Those Who Have Died From Vaccination - Page 2, updated 28 February 2013
Vaccines, BSE and vCJD In Memory of Andy Black - WARNING, GRAPHIC PHOTOS, DON'T LOOK IF EASILY UPSET - updated 2 August 2012
Vaccination: An Ecological Disaster Environmental Reasons Why Vaccines Aren't so Great. 2% of World HIV Cases Caused By Vaccines. NEW PAGE.
Skewed Statistics How Studies are 'Doctored' to Make Vaccines Seem More Effective - NEW page! updated 8 August 2012
Youth Page Under 18's Page - Know Your Vaccination Rights - Updated 25 June 2012
Take Vaccines Out of Schools Campaign! Example letters you can use to complain about the use of vaccination in schools - updated 23 June 2012
Vaccines Didn't Save Us From Smallpox Historical Evidence Against Vaccination and Historical Vaccine Death Cases
Jo's Home Education Resource Page Home Educated Kids are Rarely at Home! - updated 3 June 2012
A Parent's Guide for Pro-Vaccine Pediatricians NEW PAGE - Countering Pro-Vaccine Arguments, 30th April 2012
Rotavirus Vaccine Rotavirus Vaccine Planned for UK Babies Next Year
Paracetamol (Acetaminophen), Ibuprofen and Vaccines New Page
Vaccine Books VAN UK Shop - updated 12 September 2009
Donate To VAN UK to Keep This Website Running! Donate To VAN UK to Keep This Website Running!
Letters To VAN UK About vaccination and it's affects - updated 25 June 2012
Guest Book Comments are Moderated (Polite Messages Only)- Moderated 10 May 2013).
Contact Us Contact Us - updated 30 January 2013

Delaying Vaccination Cuts Asthma Risk (and Other Allergies Related to Vaccines).

Background

Early childhood immunizations have been viewed as promoters of asthma development by stimulating a TH2-type immune response or decreasing microbial pressure, which shifts the balance between TH1 and TH2 immunity.
Objective

Differing time schedules for childhood immunizations may explain the discrepant findings of an association with asthma reported in observational studies. This research was undertaken to determine whether timing of diphtheria, pertussis, tetanus (DPT) immunization has an effect on the development of childhood asthma by age 7 years.
Methods

This was a retrospective longitudinal study of a cohort of children born in Manitoba in 1995. The complete immunization and health care records of cohort children from birth until age 7 years were available for analysis. The adjusted odds ratio for asthma at age 7 years according to timing of DPT immunization was computed from multivariable logistic regression.
Results

Among 11, 531 children who received at least 4 doses of DPT, the risk of asthma was reduced to ½ in children whose first dose of DPT was delayed by more than 2 months. The likelihood of asthma in children with delays in all 3 doses was 0.39 (95% CI, 0.18-0.86).
Conclusion

We found a negative association between delay in administration of the first dose of whole-cell DPT immunization in childhood and the development of asthma; the association was greater with delays in all of the first 3 doses. The mechanism for this phenomenon requires further research.
Key words: DPT combination vaccine, childhood asthma, retrospective birth cohort, administrative health data
Abbreviations used: DaPT, Diphtheria, acellular pertussis, tetanus, DPT, Diphtheria, pertussis, tetanus, ICD-9, International Classification of Diseases, Ninth Revision, MIMS, Manitoba Immunization Monitoring System, MHSIP, Manitoba Health Services Insurance Program, OR, Odds ratio.

Source: Delay in diphtheria, pertussis, tetanus vaccination is associated with a reduced risk of childhood asthma, The Journal of Allergy and Clinical Immunology, Volume 121, Issue 3, Pages 626-631 (March 2008).

Put in plain English!

Researchers gave 11,531 babies four doses of the DPT vaccine.

5,000 of these babies started their jabs at 2 months old and 13.8% of them developed asthma.

In the babies who were 4 months old or older at the time of their first vaccination, there were only 5.9% who developed asthma.

The study also found a decreased incidence of asthma if the subsequent doses were delayed, but the strongest evidence for this was with the first dose.

The journal revealed that a staggering 12% of children go on to develop asthma after vaccination.

In spite of this evidence, they do not intend to change the vaccination schedule.

Parents of Unvaccinated Children Report Less Asthma

WOW! A study which looks at the health of the unvaccinated - this is 2nd study I have read on the subject. Doctors don't normally study the unvaccinated

Background

In the last 3 decades, there has been an unexplained increase in the prevalence of asthma and hay fever.
Objective

We sought to determine whether there is an association between childhood vaccination and atopic diseases, and we assessed the self-reported prevalence of atopic diseases in a population that included a large number of families not vaccinating their children.
Methods

Surveys were mailed to 2964 member households of the National Vaccine Information Center, which represents people concerned about vaccine safety, to ascertain vaccination and atopic disease status.
Results

The data included 515 never vaccinated, 423 partially vaccinated, and 239 completely vaccinated children. In multiple regression analyses there were significant (P < .0005) and dose-dependent negative relationships between vaccination refusal and self-reported asthma or hay fever only in children with no family history of the condition and, for asthma, in children with no exposure to antibiotics during infancy. Vaccination refusal was also significantly (P < .005) and negatively associated with self-reported eczema and current wheeze. A sensitivity analysis indicated that substantial biases would be required to overturn the observed associations.
Conclusion

Parents who refuse vaccinations reported less asthma and allergies in their unvaccinated children. Although this relationship was independent of measured confounders, it could be due to differences in other unmeasured lifestyle factors or systematic bias. Further research is needed to verify these results and investigate which exposures are driving the associations between vaccination refusal and allergic disease. The known benefits of vaccination currently outweigh the unproved risk of allergic disease.

Nashville, Tenn, London, United Kingdom, and Chicago, Ill
Key words: Immunization, asthma, allergic rhinitis, eczema, prevalence, cross-sectional survey
Abbreviations used: DTP, Diphtheria, tetanus, and pertussis, HiB, Haemophilus influenzae B, MMR, Measles, mumps, and rubella, NVIC, National Vaccine Information Center, RR, Rate ratio.

Source: The Journal of Allergy and Clinical Immunology, Volume 115, Issue 4, Pages 737-744 (April 2005).

VAN UK'S Comment: I have no doubt that lack of antibiotics and antipyretics would also decrease asthma and is a factor in addition to non-vaccination, however, other studies have linked vaccination with asthma, so this shouldn't be ignored.

As a mother of unvaccinated children I can say that if my child was having difficulty breathing, I most certainly would get him seen by a doctor, as would other mothers, so I don't think the low asthma rate is due to not reporting to the GP

Vaccines Cause Auto-Immune Disease

Infectious agents contribute to the environmental factors involved in the development of autoimmune diseases possibly through molecular mimicry mechanisms. Hence, it is feasible that vaccinations may also contribute to the mosaic of autoimmunity.

Vaccines are a prototypic source for natural immune stimulation, but may be involved in pathogenic disease in the setting of aberrant immune system function. Possibly, the burden on the immune system resulting from simultaneous multiple vaccines and even the different types of vaccines may also be an overwhelming challenge in the autoimmune prone individual (Shoenfeld et al., 2008). In this review, we discuss the evidence for the development of autoimmune diseases following infections.

In studies of more than 10 patients, the reported manifestations following hepatitis B vaccination were arthritis, thrombocytopenia, demyelinating encephalitis, and demyelinating neuropathy. A case-control study of 265 newly diagnosed lupus patients did not show that HBV vaccine was a risk factor for developing SLE [odds ratio (OR)-1.4] (Schattner, 2005). In a current study, 10 lupus patients were diagnosed within several days and up to one year following hepatitis B vaccination (Agmon-Levin et al., 2009). Previously, 11 cases were reported in the literature regarding the onset or exacerbation of SLE post hepatitis B vaccination (Schattner, 2005).

In concordance, a latency period of less than one week and up to 2 years between vaccination and SLE onset was reported. The classical period between vaccination and autoimmunity was considered to be several weeks, similarly to the time frame suggested in the past for post-infectious autoimmunity phenomena. Interestingly, in this case series, 70% of patients continued their immunization protocol although adverse events were documented. Similarly, in previously reported cases, the affected subjects continued to be vaccinated and aggravation of their condition by additional doses had been documented (Agmon-Levin et al., 2009). Overall, SLE patients presented post hepatitis B vaccination with mild to moderate disease and without life threatening organ involvement.

Multiple sclerosis

Neurological manifestations are common following vaccinations (Huynh et al., 2008). In a case-control epidemiological study for serious adverse events reported in the hepatitis B vaccination exposed group compared to those that received tetanus vaccine, MS was prominent with an odds ratio of 5.2 (P<0.0003). Optic neuritis was also very commonly encountered (OR-14, p< 0.0002) (Geier et al., 2005).

Guillain-Barré syndrome

In GBS, activated macrophages invade intact myelin sheaths resulting in myelin damage and demyelination (Vucic et al., 2009).

Vaccines reported as associated with GBS are diverse (Schonberger et al., 1979; Hemachudha et al., 1988; Khamaisi et al., 2004; CDC, 2006; Slade et al., 2009; Haber et al., 2009). The evidence of casual relationship with GBS is strongest with the swine flu (H1N1) vaccine that was used in 1976-7. An increased relative risk [relative risk (RR)-4-8] to develop GBS 6-8 weeks after the injection was encountered in the vaccinated group compared to the non vaccinated group. The risk for GBS was slightly less than 1 excess case of GBS per 100,000 vaccinated individuals, and hence the vaccine program was suspended (Schonberger et al., 1979). Further studies substantiated the association between the H1N1 vaccine and an increased relative risk (RR-7/1) for GBS 6 weeks after the vaccine (Safranek et al., 1991). The pathophysiology is unclear but may be related to vaccine induced anti-ganglioside antibodies (GM1) (Nachamkin et al., 2008).

The vaccine against Neisseria meningitides is for use among individuals aged 11-55 years old. The VAERS published a warning of a possible association between the Meningococcal Polisaccharide Diphteria Toxoid Conjugated Vaccine (MCV4) and GBS, because of 5 cases of GBS following the MCV4 vaccine, and later 12 additional cases were reported (CDC, 2005). Based on reports, statistical analysis did not show any significant increase in the rate of GBS occurring 6 weeks after the MCV4 vaccine compared to non-vaccinated population. However, it is recommended that individuals with a history of GBS should not be vaccinated with MCV4 unless they are in a high risk for meningococcal infection.

Vaccine induced myopathies

The reports on vaccine induced inflammatory myopathies are sporadic and include cases of following immunization with HBV, bacillus Calmette-Guérin, tetanus, influenza, smallpox, polio, diphtheria, or combinations with diphtheria (Orbach et al., 2009). There is no statistically significant increase in the incidence of polymyositis or dermatomyositis after any mass vaccination. Among 289 patients with inflammatory myopathies followed in the Mayo Clinic, no recent immunization was recorded (Winkelman, 1968; Winkelmann, 1982).

Macrophagic myofasciitis

Macrophagic myofasciitis is a reaction to intramuscular injections of vaccines containing aluminum hydroxide as an adjuvant and affects mainly adults. The symptoms are usually myalgia, arthralgia, asthenia and, less frequently, muscle weakness and fever, in the presence of elevated creatine kinase and erythrocyte sedimentation rates. The electromyogram has a unique pathologic pattern characterized mainly by focal infiltration of the epimysium, perimysium, and perifascicular endomysium by sheets of large, non-epithelioid macrophages, which show fine granular staining for periodic acid-Schiff (PAS) stain that appear as small, osmiophilic, spiky structures on electron microscopy, representing the aluminum hydroxide crystals (Gherardi et al., 2001). Immunizations containing aluminum may trigger Macrophagic myofasciitis in the context of an HLA-DRB1*01 genetic background (Guis et al., 2002). Frequently, patients improve with steroid therapy.

Vasculitis

Numerous case reports reported a possible association between polyarteritis nodosa (PAN) and hepatitis B vaccination. Overall, 25 cases of PAN were submitted to VAERS over an 11 year period until 2001. Among them, only 10 individuals were diagnosed as definite or possible PAN and are discussed here. The median age of patients was 45 years old and 5 patients were hospitalized. A modal peak of 2 weeks and median of 2.8 weeks post-vaccination was noted. All cases received at least 2 doses of vaccine prior to symptom onset. Hepatitis B surface antigenemia frequently follows hepatitis B vaccination and is detected many days after the 20 microgram vaccine. This could explain related immune-complex disease. Recently, there were less than 20 reports on the development of vasculitis following influenza vaccination. Small, medium, and large vessels were involved (Begier et al., 2004). All in all, this would be considered a rare event.

Rheumatoid arthritis

A total of 48 out of 898 (5.3%) of patients with early inflammatory polyarthritis reported an immunization in the 5 weeks prior to symptom onset. There were no important clinical or demographic differences between the 48 immunized patients and 185 consecutive patients who did not report prior immunization. The frequencies of HLA DRB1 *01 and *04 and the shared epitope in 33 of the immunized patients were no different in the non- immunized patients compared to healthy controls. Possibly, in a small number of susceptible individuals, immunization may act as a trigger for RA (Harrison et al., 1997).

HPV vaccine and autoimmune manifestations

The recently released vaccine for human papillomavirus (HPV) offers an opportunity to assess the development of autoimmune phenomena in a high risk population of young women. Hence, we chose to investigate and report separately on this vaccine.

Recently developed vaccines against human papillomavirus (HPV) and hepatitis B virus (HBV) contain a novel Adjuvant System, AS04, which is composed of 3-O-desacyl-4′ monophosphoryl lipid A and aluminum salts. All randomized, controlled trials of HPV-16/18, herpes simplex virus (HSV), and HBV vaccines were analyzed in an integrated analysis of individual data (N = 68,512). A separate analysis of the HPV-16/18 vaccine trials alone was also undertaken (N = 39,160). The reported rates of overall autoimmune events were around 0.5% and did not differ between the AS04 and control groups. The relative risk (AS04/control) of experiencing any autoimmune event was 0.98 (95% confidence intervals 0.80, 1.21) in the integrated analysis and 0.92 (0.70, 1.22) in the HPV-16/18 vaccine analysis. This integrated analysis of over 68,000 participants who received AS04 adjuvant vaccines or controls demonstrated a low rate of autoimmune disorders, without evidence of an increase in relative risk associated with AS04 adjuvanted vaccines (Verstraeten et al., 2008).

In the Danish Civil Registration system, among approximately half a million adolescent girls, 414 autoimmune disorders were listed. The 5 most common autoimmune diseases occurring within 6 weeks of vaccination among 100,000 girls were: type I diabetes, juvenile arthritis, Crohn’s disease, Henoch-Schonlein disease, and ulcerative colitis (Sutton et al., 2009).

A most probable causality occurred between exposure to swine flu vaccine and the development of GBS. In addition, MMF occurred following exposure to aluminum containing adjuvant. Vaccines, like infections, activate immune mediated mechanisms to induce a protective effect. Hence, a complex vaccine may theoretically be more immunogenic than a simple vaccine. Vaccines harbor added complex agents, for example, adjuvants including aluminum, which may induce autoimmune disease. Preservatives are more often found in viral vaccines compared to bacterial vaccines suggesting that the preservatives may be the inciting culprits (Israeli et al., 2009).

A comprehensive strategy is required to develop a new vaccine that will not induce autoimmune manifestations as previously proposed.

Perhaps, the assessment of autoantibody and HLA status prior to immunization will serve as a marker for individuals at risk. More research is required to identify those individuals who may develop autoimmune diseases following immunizations.

Source: http://www.discoverymedicine.com/Hedi-Orbach/2010/02/04/vaccines-and-autoimmune-diseases-of-the-adult/

Vaccines Cause Early onset Epilepsy but Ever so Caring Health Chiefs want to Vaccinate Anyway

Childhood vaccines may trigger early onset of a severe form of infant epilepsy, but researchers say the disorder is ultimately caused by defective genes and lifesaving vaccines should not be withheld from these children.

The researchers said they feared the study published in the Lancet medical journal would scare parents away from getting their children vaccinated but stressed the babies in the study would likely have developed seizures within months regardless of the vaccine.

The disorder, called Dravet syndrome, generally begins with seizures around six months of age. These children have poor language and motor skills and difficulty relating to others.

Up to 80 percent of them have mutations in the SCN1A gene.

Anne McIntosh of the University of Melbourne's Epilepsy Research Center and colleagues examined the medical records of 40 Dravet syndrome patients with the genetic mutation who had been vaccinated against whooping cough, or pertussis.

They said 30 percent of these children developed their first seizures within two days of receiving the vaccine but symptoms of their disorder were no worse than the other children who had their first seizures later on.

"In about 30 percent of people, it appears that (first seizures) came on rather quickly after the vaccination.

Source: Reuters Health, 4 May 2010.

VAN UK'S Comment: A classic technique, doublespeak. The vaccine caused the immune system to go over the edge, therefore it was the vaccine!

Effects of diphtheria-tetanus-pertussis or tetanus vaccination on allergies and allergy-related respiratory symptoms among children and adolescents in the United States

Findings from animal and human studies confirm that diphtheria and tetanus toxoids and pertussis (DTP) and tetanus vaccinations induce allergic responses; associations between childhood vaccinations and subsequent allergies have been reported recently.

OBJECTIVE:

The association of DTP or tetanus vaccination with allergies and allergy-related respiratory symptoms among children and adolescents in the United States was assessed.

METHODS:

Data were used from the Third National Health and Nutrition Examination Survey on infants aged 2 months through adolescents aged 16 years. DTP or tetanus vaccination, lifetime allergy history, and allergy symptoms in the past 12 months were based on parental or guardian recall. Logistic regression modeling was performed to estimate the effects of DTP or tetanus vaccination on each allergy.

RESULTS:

The odds of having a history of asthma was twice as great among vaccinated subjects than among unvaccinated subjects (adjusted odds ratio, 2.00; 95% confidence interval, 0.59 to 6.74). The odds of having had any allergy-related respiratory symptom in the past 12 months was 63% greater among vaccinated subjects than unvaccinated subjects (adjusted odds ratio, 1.63; 95% confidence interval, 1.05 to 2.54). The associations between vaccination and subsequent allergies and symptoms were greatest among children aged 5 through 10 years.

CONCLUSIONS:

DTP or tetanus vaccination appears to increase the risk of allergies and related respiratory symptoms in children and adolescents. Although it is unlikely that these results are entirely because of any sources of bias, the small number of unvaccinated subjects and the study design limit our ability to make firm causal inferences about the true magnitude of effect.

Source: J Manipulative Physiol Ther. 2000 Feb;23(2):81-90 - http://www.ncbi.nlm.nih.gov/pubmed/10714532

Self-Organized Criticality Theory of Autoimmunity

Methodology/Principal Findings

Repeated immunization with antigen causes systemic autoimmunity in mice otherwise not prone to spontaneous autoimmune diseases. Overstimulation of CD4⁺ T cells led to the development of autoantibody-inducing CD4⁺ T (aiCD4⁺ T) cell which had undergone T cell receptor (TCR) revision and was capable of inducing autoantibodies. The aiCD4⁺ T cell was induced by de novo TCR revision but not by cross-reaction, and subsequently overstimulated CD8⁺ T cells, driving them to become antigen-specific cytotoxic T lymphocytes (CTL). These CTLs could be further matured by antigen cross-presentation, after which they caused autoimmune tissue injury akin to systemic lupus erythematosus (SLE).

Conclusions/Significance

Systemic autoimmunity appears to be the inevitable consequence of over-stimulating the host's immune ‘system’ by repeated immunization with antigen, to the levels that surpass system's self-organized criticality.

Source: Tsumiyama K, Miyazaki Y, Shiozawa S (2009) Self-Organized Criticality Theory of Autoimmunity. PLoS ONE 4(12): e8382. doi:10.1371/journal.pone.0008382 - Tsumiyama K, Miyazaki Y, Shiozawa S (2009) Self-Organized Criticality Theory of Autoimmunity. PLoS ONE 4(12): e8382. doi:10.1371/journal.pone.0008382

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