Diseases In The Vaccinated
"Official data have shown that the large-scale vaccinations undertaken in the US have failed to obtain any significant improvement of the diseases against which they were supposed to provide protection." Dr A. Sabin, developer of the Oral Polio vaccine
Dr A. Sabin, developer of the Oral Polio vaccine (lecture to Italian doctors in Piacenza, Italy, December 7th 1985)
Whooping Cough In The Vaccinated
Whooping Cough Increases 49% Since 1980's In The Vaccinated Despite Increasing Number Of Shots
Reported cases of pertussis among adolescents and adults have increased since the 1980s, despite increasingly high rates of vaccination among infants and children. However, severe pertussis morbidity and mortality occur primarily among infants.
The incidence of reported cases of pertussis among infants increased 49% in the 1990s compared with the incidence in the 1980s (19 798 vs 12 550 cases reported; 51.1 cases vs 34.2 cases per 100 000 infant population, respectively). Increases in the incidence of cases and the number of deaths among infants during the 1990s primarily were among those aged 4 months or younger, contrasting with a stable incidence of cases among infants aged 5 months or older. The proportion of cases confirmed by bacterial culture was higher in the 1990s than in the 1980s (50% and 33%, respectively); the proportion of hospitalized cases was unchanged (67% vs 68%, respectively). Receipt of fewer doses of vaccine was associated with hospitalization, when cases were stratified by age in months.
Despite High Vaccination Coverage Whooping Cough Is Endemic In The Netherlands
Despite the introduction of large-scale pertussis vaccination in 1953 and high vaccination coverage, pertussis is still an endemic disease in The Netherlands, with epidemic outbreaks occurring every 3-5 years." One factor that might contribute to this is the ability of pertussis strains to adapt to vaccine-induced immunity, causing new strains of pertussis to re-emerge in this well-vaccinated population.
(Journal of Infectious Diseases, vol. 179, April 1999; 915-923).
One in Five Vaccinated Children Will Still Get Whooping Cough
Just recently, Dr. Kari Simonsen, a pediatrician at the University of Nebraska Medical Center, USA, said one in five children who are vaccinated for whooping cough will still get the disease. She said efficacy of the vaccine was 'comparatively low', but said
'It's the best vaccine we can build to date.'
Despite admitting this, she still believes that parents should get the vaccine for their children.
At St. Robert Bellarmine School in west Omaha, 12 children had confirmed whooping cough, of those, most had been vaccinated.
The Nebraska Department of Health and Human Services reported Thursday that the state has had 117 confirmed cases this year, up from 70 all of last year and 99 in 2006. There were 312 cases in Nebraska in 2005.
In Douglas County, 48 cases have been reported this year. Last year, 21 cases were reported.
This is in a country that gives five doses of the vaccine in the first four years of life and then another dose at 11 years of age!
(Omaha World Herald, 'Vaccine Didn't Stop Whooping Cough', 31st October 2008).
Recently Vaccinated People Are Becoming Sick Anyway And Can Pass The Bacteria On To Others And Make Them Sick
Victor Plotkin - an epidemiologist from Lake County in the US has reported that there have been 82 cases of pertussis in the county so far this year.
'Plotkin said the county did see very high numbers of cases during a nationwide outbreak of pertussis in 2004 and 2005. In 2004, there were 152 cases of pertussis and 135 cases in 2005. However, before that, pertussis cases in the county had averaged about 8 to 10 a year for many years.
Plotkin said the 2004 and 2005 pertussis outbreak appears that it may have been attributed to waning immunity among older children and adults who had not received booster shots. He said the most recent outbreak is a bit more puzzling because many of the children who are becoming ill are younger children who were recently vaccinated.
"Unfortunately, during this outbreak, even people that have been recently vaccinated are becoming sick anyway," he said. "Their symptoms are milder, but they still can pass the bacteria along to others and make others sick."
(Whooping Cough Increases in Lake County - the Vernon Hills Review 20th November 2008).
No Protection Is Demonstrable In Infants Following DPT
'Calculations based on the mortality of whooping-cough before 1957 predict accurately the subsequent decline and the present low mortality
Incidence [is] unaffected either by small-scale vaccination beginning about 1948 or by nationwide vaccination beginning in 1957
No protection is demonstrable in infants.'
(The Lancet, vol. 1, January 29, 1977, pp. 234-7).
Whooping Cough Rise Despite 90% Vaccination Rate
TASMANIA is in the grip of the worst outbreak of whooping cough for at least a decade.
The Public and Environmental Health Service has been notified of 146 cases of the disease, which is potentially fatal, particularly for babies and young children.
Parents who have not had their children immunised have been advised to act immediately.
The outbreak, concentrated in the South of the state, represents more than double the number of cases for the whole of last year (56).
Director of Public Health Mark Jacobs said: "Most of the cases have occurred in July and August. The August notifications exceeded the total for last year."
There have been 122 reported cases in the South, 16 in the North and eight in the North-West.
'Our most recent figures show that about 90% of children are immunised by the time they reach their first birthday," Dr Jacobs said.
9th September 1999 - The Mercury. Written by Sean Stevenson.
DIPHTHERIA IN THE VACCINATED
Health Ministry Concerned About Why Inoculations Failed To Work
Ukraine's diphtheria inoculation campaign last year has failed to provide nation-wide protection. Last week, the Ukrainian Ministry of Health revealed that, in the first 5 months of this year, some 1350 cases of the disease had been reported, of whom 15 died. Although the total is 510 less than for the same 5 months in 1995, the Ministry is clearly concerned about why the inoculations failed to work, and has launched a special investigation. One explanation that has been put forward is that vaccines received from western programmes of humanitarian aid are "not very effective".
The break-up of the Soviet Union left Ukraine without a drug industry of its own, thus its health service is largely dependent on donations. Such an allegation, even if eventually proved unfounded, could provide a weapon to politicians who oppose closer ties between Ukraine and western Europe.
(The Lancet, 15/6/96, Vol 347, p.1686).
Respiratory diphtheria among highly vaccinated military trainees in Latvia. 85% Had More Than 5 Vaccines! Mild Diphtheria Can Occur In Vaccinated People Living In Overcrowded Conditions
An outbreak of respiratory diphtheria occurred among highly-vaccinated trainees at a Latvian military academy in August September 2000. We reviewed immunization, clinical and laboratory records and administered a questionnaire to obtain data on exposure factors. Among 207 trainees, 45 (22%) diphtheria cases and 79 (38%) carriers of toxigenic Corynebacterium diphtheriae were identified. All patients survived; 1 had severe myocarditis. Sharing cups was a risk factor for infection. Over 85% of trainees had received ≥5 doses of diphtheria toxoid. Neither infection nor disease was associated with the number of doses or interval since last dose. However, the risk of disease was lower and diphtheria antitoxin levels were higher among trainees who received their last booster dose with higher-antigen diphtheria toxoid (DT) instead of lower-antigen Td. Outbreaks of mild diphtheria can occur among highly-vaccinated persons living in crowded conditions with intense exposure; high-antigen diphtheria booster-vaccination might provide better protection under these conditions.
Source: Scandinavian Journal of Infectious Diseases, Volume 37, Numbers 11-12, -12/November 2005 , pp. 813-820(8)
DIPHTHERIA IN A VACCINATED ADULT IN BRAZIL- 30% OF FATAL CASES ARE IN THE VACCINATED
In 1999, a case of diphtheria in a 32-year-old woman was reported. The patient developed a sore throat immediately after participating of a five-day meeting with European workers in Rio de Janeiro. Her history included complete pediatric immunization (DTP) and three doses of adult formulation tetanus and diphtheria toxoid (dT) two years earlier. Clinical diagnosis of diphtheria was not made until microbiologic examination of specimens confirmed toxigenicity of Corynebacterium diphtheriae var. gravis, a biotype currently found circulating within Europe where diphtheria remains epidemic. This case reinforces the potential susceptibility of Brazilian adults to epidemic diphtheria in the vaccine era.
Epidemic diphtheria may occur despite fairly high levels of childhood coverage. The worst epidemic of diphtheria in postvaccination era (³ 157,000 cases and 5,000 deaths) demonstrated conclusively the potential susceptibility of adults to epidemic diphtheria in the vaccine era. In 1990, diphtheria reemerged in the Russian Federation and spread to all Newly Independent States (NIS) with a high proportion of cases in adults, 64% to 82%, respectively. Severe disease and a high percentage (30%) of fatal cases were documented among vaccinated individuals (2,14).
The spread of epidemic seemed facilitated by large scale population movements; socioeconomic instability, partial deterioration of health infrastructure; delay in implementing measures to control epidemic; inadequate information for physicians and the public; lack of adequate supplies for prevention and treatment in most of the countries (2,8).The reasons for reemergence of epidemic diphtheria in countries where immunization programs had nearly eliminated diphtheria are not fully understood but are thought to include the introduction of toxigenic C. diphtheriae strains of a new biotype into the general population, besides low coverage with diphtheria vaccine among children and large gap of immunity among adults (4,22).
Despite the success of mass immunization in many countries diphtheria remains a serious health problem within many regions of the world.
Tetanus In An 'Immunized' Patient
Israeli researchers present the case of a 34-year-old construction worker who was hospitalized after having a reported epileptic fit and experiencing flu-like symptoms. The patient had a low-grade fever, but was alert and coherent. Any attempts to speak or get up on the second day resulted in attacks of risus sardonicus, opisthotonus, and trismus. The patient was diagnosed with tetanus and given 2000 U of human tetanus immunoglobulin. Further treatment was provided, and after 15 days, the patient had stopped taking diazepam and ventilatory support was withdrawn. The man had been fully immunized against tetanus, and had received booster shots five and two years before being hospitalized.
British Medical Journal Online (10/16/99) Vol. 319, No. 7216, P. 1049.
Cephalic Tetanus In An 'Immunized' Patient
A case of cephalic tetanus that occurred in a fully immunized patient is described. An 18-year-old man presented with bilateral facial spasms, without trismus or more generalized involvement, followed by facial weakness. The difficulties in clinical diagnosis and the contribution of electrophysiological studies to the management of such patients are highlighted. The variable level of protection that is conferred by immunization is discussed.
Med J Aust. 1986 Aug 4-18;145(3-4):156-7.
Case report of tetanus in an immunized, healthy adult
We report the case of a 58-year-old man born in the United States with a history of complete childhood immunizations who presented to the Emergency Department with trismus. Past medical history was significant only for Elephantiasis. After an exhaustive workup the patient was found to have Tetanus, with no identifiable portal of entry. The patient was successfully treated for Tetanus with complete recovery. Tetanus is caused by the organism Clostridium Tetani, which usually requires an open lesion to cause infection. Our patient was unique in that he was previously immunized with no obvious lesion. Tetanus should be suspected and treated empirically in any patient presenting with typical signs and symptoms even without an apparent entry site.
Nottingham Girl Gets Tetanus Despite Being Vaccinated
Tyla Green of Clifton, Nottingham, had been immunised but doctors believe that she got tetanus when she cut her foot five weeks ago.
After four weeks in the Queen's Medical Centre, Nottingham, she has returned home and is expected to make a full recovery in six months. Her mother Halima, 34, who has three other daughters aged from 9 to 13, said yesterday: "We are overjoyed to have Tyla home. We have gone to hell and back, but even though she still can't speak she can laugh and that means the world to us."
Mrs Green said that Tyla had been sent home from school ill and two days later was found disorientated at home. "When I picked her up she went rigid and started having a sort of a fit."
Her husband Shane, 39, called an ambulance and Tyla was taken to hospital. Mrs Green said that doctors suspected that Tyla had meningitis, then another brain virus, until she developed a locked jaw, a classic sign of tetanus. "A doctor asked if she had cut herself. At that time, I didn't think she had, but I learnt later that she had trodden on something which really hurt her foot about a week before she became ill.
"Because it wasn't pouring blood or needed stitches I dismissed it. Tyla was always running around with nothing on her feet. I would advise all parents to make sure their children have something on their feet whenever they are outside."
Tetanus is caused by bacteria that attack the central nervous system. It is extremely rare. There were only three cases, all in adults, in England and Wales last year.
Tyla is the first child under 15 to contract the disease since 1989 and hers is thought to be the first child case in Nottingham for more than 20 years.
Her consultant paediatrician, Martin Hewitt, said: "You can easily die from tetanus but this young lady has made a remarkable recovery. She was desperately ill but I expect her to make a full recovery."
He said it was rare for someone who had been immunised to get the disease but it was possible. "It depends on whether the level of antibodies you have are sufficient to fight the infection," he said.
Tyla would probably need speech therapy, physiotherapy and occupational therapy in the coming months before making a complete recovery, Mr Hewitt said.
Dr Richard Sack, consultant for communicable diseases at Nottingham Health Authority, said that the chance of anyone developing tetanus from a wound after being vaccinated was extremely low.
The Times 14th August 2000.
Most Polio Victims Were Vaccinated - 201 out of 203 cases were vaccinated
Out of the total 203 cases of polio reported from across the country this year, 201 had received polio vaccines. This was stated by the Health Ministry in a reply in Parliament.
While this raises doubts about the efficacy of the polio drops, Health Ministry officials said this could have happened due to inadequate intake of the vaccine.
A senior official in the World Health Organisation also said: This could have happened as they may not have got enough polio drops to develop full immunity.
A Health Ministry official also said that the nutritional status of the child should also be considered. Undernourished children cannot produce good antibodies. As a result, the vaccine becomes ineffective. About 54.3 per cent children are victims of malnutrition and hence the failure rate, he said.
Apart from malnutrition, high population density, overcrowding, poor sanitation and ignorance contribute to the high incidence of polio in the state.
Quoting a latest study by the Indian Council of Medical Research (ICMR) in Moradabad, the official said: According to them, children above three years of age in Moradabad are well protected from polio as they have received adequate doses. However, children from 6-12 months are not receiving adequate doses. The international health agencies say that a child should get at least 15-16 doses to develop full immunity against the disease, he said.
Indian Express 1st May 2008.
New Polio Cases Cast Doubt On Vaccination
Confirmation that three children in Punjab Province, the most developed in the country, have contracted polio takes the total number of cases detected this year to 80.
So far 22 cases have surfaced in Punjab, 31 in the North West Frontier Province, 15 in the southern province of Sindh, seven in the southwestern province of Balochistan, and five in the federal capital, Islamabad.
According to the World Health Organization (WHO), 32 cases of polio were detected in 2007, and 40 in 2006.
The high incidence in the Punjab is leading to concerns about the vaccine itself, with newspaper reports alleging it is of low-quality, or that expired vaccines are being used.
Each of the three children who have become the latest victims of the potentially crippling polio virus - Zunaira aged 14 months in Okara, Saima, aged two years in Bahawalpur, and Asad Ali, aged 18 months in Kasur - had reportedly received multiple doses of the vaccine.
Humanitarian News and Analysis. UN Office for Humanitarian Affairs. 19th October 2008.
The Only Cases Of Polio Since 1979 Were Caused By The Vaccine
'The last case of poliomyelitis in the United States due to indigenously acquired wild poliovirus occurred in 1979; however, as a consequence of oral poliovirus vaccine (OPV) use that began in 1961, an average of 9 cases of vaccine-associated paralytic poliomyelitis (VAPP) were confirmed each year from 1961 through 1989. To reduce the VAPP burden, national vaccination policy changed in 1997 from reliance on OPV to options for a sequential schedule of inactivated poliovirus vaccine (IPV) followed by OPV. In 2000, an exclusive IPV schedule was adopted.'
From 1990 through 1999, 61 cases of paralytic poliomyelitis were reported; 59 (97%) of these were VAPP (1 case per 2.9 million OPV doses distributed), 1 case was imported, and 1 case was indeterminate. Thirteen cases occurred during the 1997-1999 transitional policy period and were associated with the all-OPV schedule; none occurred with the IPV-OPV schedule. No cases occurred after the United States implemented the all-IPV policy in 2000. The last imported poliomyelitis case occurred in 1993 and the last case of VAPP occurred in 1999.
Conclusion The change in polio vaccination policy from OPV to exclusive use of IPV was successfully implemented; this change led to the elimination of VAPP in the United States.'
Polio Occuring As A Consequence Of Diphtheria Vaccination
Dr. Geffen in London UK described 30 children under the age of 5 who had been vaccinated with diphtheria and/or whooping cough vaccines and went on to develop polio within 4 weeks of the vaccines.
'The paralysis affecting, in particular, the limb of injection. In 7 other recently vaccinated cases, paralysis occured but not in the limb that had received the injection'.
Bradford Hill, A., Knoweldon, J. 1950. "Inoculation and Poliomyelitis". BMJ, July 1st, pp 1-6.
Department of Health in 1950 Recommended That Diphtheria And Multiple Vaccines Not Be Used In Areas Where There Was Polio
it was reported that of 112 cases of paralysis admitted to the Park Hospital, London, during 1947-1949, 14 were paralyzed in the limb which had received one or more of a course of immunizing injections within the previous two months. In the majority of cases, the interval between the last injection and the onset of paralysis was between 9 and 14 days. Again, combined whooping cough, diphtheria and tetanus injections were involved. This outbreak of polio followed an intensive immunization campaign during that time, 1947-49. Following these findings, the Ministry of Health recommended that diphtheria and triple vaccines should not be used in areas where polio was naturally present. From that time onwards, the incidence of paralytic polio decreased rapidly in Britain, even prior to the advent of Salk vaccination..."
BMJ., July 29th, 1950.
Incidence of Polio Statistically Greater In the Recently Vaccinated Than In The Unvaccinated
Following a polio epidemic in 1949 a scandal broke in Britain after it was discovered that children were getting polio after being vaccinated against diphtheria and whooping cough with symptoms of paralysis showing in the vaccinated limb within 28 days of the first injection.
The Archives of Disease in Childhood reported 17 cases of polio after various injections.
Martin, J.K. 1950. "Local paralysis in children after injections" Arch. Dis. Childhood, March 1950, pp 1-5.
69 Vaccinated Children Get Polio From The Vaccine. Excreted Vaccine Polio Virus Ends Up In Water Supply And Can Spread And Infect Unvaccinated Children
A polio outbreak in Nigeria was caused by the vaccine designed to stop it, international health officials say, leaving at least 69 children paralyzed. The CDC and the World Health Organization announced the cause of the polio outbreak last week, even though they knew about it last year.
Outbreaks caused by the oral vaccine's live virus have happened before. But the continuing Nigerian outbreak is the biggest ever caused by the vaccine.
Officials now worry that the latest vaccine-caused Nigerian outbreak could trigger another vaccine scare.
Experts say such outbreaks only happen when too few children are vaccinated. In northern Nigeria, only about 39 percent of children are fully protected against polio.
The oral polio vaccine contains a weakened version of polio virus. Children who have been vaccinated excrete the virus, and in unsanitary conditions it can end up in the water supply, spreading to unvaccinated children.
Vaccine Associated Paralytic Polio
BACKGROUND. In Romania the rate of vaccine-associated paralytic poliomyelitis is for unexplained reasons 5 to 17 times higher than in other countries. Long ago it was noted that intramuscular injections administered during the incubation period of wild-type poliovirus infection increased the risk of paralytic disease (a phenomenon known as "provocation" poliomyelitis). We conducted a case-control study to explore the association between intramuscular injections and vaccine-associated poliomyelitis in Romania. ...RESULTS. Of the 31 children with vaccine-associated disease, 27 (87 percent) had received one or more intramuscular injections within 30 days before the onset of paralysis, as compared with 77 of the 151 controls (51 percent) (matched odds ratio, 31.2; 95 percent confidence interval, 4.0 to 244.2). Nearly all the intramuscular injections were of antibiotics, and the association was strongest for the patients who received 10 or more injections (matched odds ratio for > or = 10 injections as compared with no injections, 182.1; 95 percent confidence interval, 15.2 to 2186.4). The risk of paralytic disease was strongly associated with injections given after the oral polio virus vaccine, but not with injections given before or at the same time as the vaccine (matched odds ratio, 56.7; 95 percent confidence interval, 8.9 to infinity). The attributable risk in the population for intramuscular injections given in the 30 days before the onset of paralysis was 86 percent (95 percent confidence interval, 66 to 95 percent); that is, we estimate that 86 percent of the cases of vaccine-associated paralytic poliomyelitis in this population might have been prevented by the elimination of intramuscular injections within 30 days after exposure to oral poliovirus vaccine. CONCLUSIONS. Provocation paralysis, previously described only for wild-type poliovirus infection, may rarely occur in a child who receives multiple intramuscular injections shortly after exposure to oral poliovirus vaccine, either as a vaccine recipient or through contact with a recent recipient. This phenomenon may explain the high rate of vaccine-associated paralytic poliomyelitis in Romania, where the use of intramuscular injections of antibiotics in infants with febrile illness is common.
Strebel PM, et al. Paralytic poliomyelitis in Romania, 1984-1992. Evidence for a high risk of vaccine-associated disease and reintroduction of wild-virus infection. Am J Epidemiol. 1994 Dec 15;140(12):1111-24. PMID: 7998593; UI: 95091240.
MENINGITIS AND BLOOD POISONING
New 'Superbug' Meningitis C
Meningitis C "superbugs" that are impervious to vaccines could pose a
new threat to children, new research has claimed.
Scientists in the UK have identified three strains with heightened
resistance to vaccine-triggered immune responses.
At present there are no reports of emerging vaccine-resistant
meningitis C in the community. But experts fear if the strains get a
foothold they could undermine the vaccine, introduced into the UK in 1999.
Each year more than 2,000 people, mostly children, are affected by
all forms of meningitis in Britain. The disease claims about 300
lives per year and leaves hundreds of other victims with permanent
The authors of the new research, led by Professor Christoph Tang,
from Imperial College London, called for more studies into the
genetic changes behind vaccine resistant meningitis C.
A simple alteration in its DNA is thought to give the bug the
potential to avoid attack by immune system antibodies.
The study, published in The Journal of Experimental Medicine, was
funded by the charity Meningitis UK.
Sourced from a UK Press Google article.
VAN UK'S COMMENT: Vaccines are known to mutate and if you suppress an illness it can develop into another form of the illness. Currently the same thing is happening with prevnar causing superbug ear infections.
Meningitis Vaccinations blamed for a rise in deaths
The success of a vaccination campaign against meningitis is being
blamed for a sudden rise in the number of deaths.
Cases of meningitis and septicaemia have fallen from about 4,000 a
year in the late 1990s to 2,446 last year following the introduction
of a vaccine against meningitis C in November 1999. But in a bizarre
twist the number of deaths rose last year by 17 per cent from 317 to
370 and is not far below the level before the vaccine was introduced.
Specialists say one reason for the rise in deaths is the mistaken
belief that the vaccine protects against all forms of meningitis. The
vaccine is only effective against meningitis C, cases of which have
fallen by 90 per cent, but offers no protection against the equally
deadly meningitis B.
The Meningitis Research Foundation is to launch a campaign this week
to alert the public to the risks. A spokes-woman said: "We are
extremely concerned about the rise in deaths. With cases declining
this is the last thing we want to see. We don't know why deaths are
rising but anecdotal evidence suggests many people think that since
the introduction of the meningitis C vaccine the problem is solved."
The vaccine is given routinely to all babies in the first months of
life and has also been administered in catch-up exercises to older
children and young adults.
But the foundation says this has generated a false sense of security
among the public and led parents and individuals to ignore symptoms,
leading to delays in getting help.
"In a survey of students we found that half thought that, because they
had been vaccinated, they couldn't get meningitis. They thought they
were OK and didn't have to worry any more. Callers to our helpline
said the same thing. So many mums said they didn't think their child
could get the disease because they had been vaccinated."
The Independent 20th September 2004.
New military recruit died of meningitis shortly after being vaccinated for it.
A Marine recruit who died Dec. 15 had an overwhelming meningococcal
bacteria infection that was different from the streptococcus A that
infected 185 other recruits at the Marine Corps Recruit Depot, it was
All recruits entering MCRD are vaccinated against the meningococcal
bacteria, but the vaccine is not always effective, Malone said.
One recruit remains in critical condition from the step A-related pneumonia
outbreak that struck the depot.
More than 126 people were hospitalized with pneumonia, though not all were
related to strep A.
Despite vaccine, meningitis takes teen's life
When Bentley College freshman Erin M. Ortiz went home sick last weekend,
her mother did what any mother might do. She cooked comfort foods - corned
beef, rice, and plantains - reflecting her daughter's Puerto Rican and
"It was her favorite meal," said Brenda Rivera, a family friend.
But just hours after complaining of a headache and going to bed to sleep it
off, Ortiz, 18, was dead of bacterial meningitis, a disease against which
she had been vaccinated. Now, Ortiz's family hopes others will learn from
"I'm all cried out," said her father, Raymond Ortiz. "I've got a hole in my
heart. I don't think I'll ever be the same."
"We thought she'd be covered," he said. "They don't tell you that even if
you get the vaccine, you're still susceptible."
By Tania deLuzuriaga, Globe Staff | October 10, 2007 Boston.com news.
IRISH KIDS DEVELOP MENINGITIS DESPITE BEING VACCINATED
Three children have been hospitalised with meningitis in Ireland this year
despite being vaccinated against the disease.
Recommendations were made last July to offer meningitis boosters after it
was found that vaccinations given at two, four and six months may not be
adequate enough to fight the disease caused by the haemophilus influenzae
However, the booster programme is yet to be implemented in spite of calls
from the National Immunisation Advisory Committee (NIAC).
Consultant paediatrician at Portiuncula Hospital in Ballinasloe, Dr Kevin
Connolly, said: "I am disappointed that the implementation of a booster
programme was not advanced quicker. The NIAC scheduled extra meetings
specifically to discuss whether a booster was necessary.
"We made a decision in July in the hope that a booster dose would be
introduced before the winter period. I am very disappointed that nothing
definite has been decided thus far."
It also emerged this week that several children have suffered neurological
damage in the past few years as a result of the disease, which can also
cause septic arthritis and a fatal voice box infection.
Despite the development of a new vaccine in 1992, 14 cases of the disease
were reported in 2003, the highest number in almost ten years.
VAN UK'S COMMENT: Since the vaccine clearly didn't work and may have even contributed to the meningitis why would they think giving more ineffective vaccines would help?
Vaccine Adverse Event Reporting System Reports Of Meningitis After Hib Vaccine
VAERS ID 25493
An 18 month old boy was vaccinated with hib vaccine and 160 days later he developed pneumonia and according to diagnostic lab tests he had blood cultures positive for Haemorphilus Influenzae type B.
VAERS ID 25796
2 year old boy developed Hib blood poisoning and meningitis 310 days after hib vaccination.
He had a history of febrile seizures.
VAERS ID 25798
A 2 year old girl was given a hib vaccine and 102 days later she developed hib meningitis and had temporary paralysis of her lower limbs. Her blood culture tested positive for Haemophilus influenzae B.
VAERS ID 27261
A 6 month old baby recieved his first hib vaccination and 22 days later he was hospitalized with hib sepsis and meningitis.
VAERS ID 27274
An 18 month old girl had a hib vaccination and developed meningitis within 12 hours of the shot. Her blood culture was positive for hib.
She had had a urine infection at the time of vaccination but was otherwise healthy.
19 month old child had Hib vaccine and DPT and oral polio. 504 days later he DIED after contracting hib meningitis. His blood culture tested positive for Hib.
His father had stated he had some kind of immune system disorder prior to vaccination.
VAERS ID 27813
A 2 month old baby boy had Hib vaccine DPT and oral polio vaccines.
He developed hib meningitis and sepsis 10 days after vaccination.
VAERS ID 233312
A 4 month old boy was vaccinated with DTaP Hib and pneumonia vaccines.
36 days later he was hospitalized with hib meningitis and pneumonia. His blood culture tested positive for hib.
Recent 2008 VAERS Failure Reports
A 2 month old boy was vaccinated with DTAP HIB IPV PNC and ROTHB5 vaccines on 3rd April 2008.
3 days later he developed pneumococcal meningitis and bacteremia.
He had been born at 33 weeks.
VAERS ID 320337
A 5 month old boy was vaccinated with hib vaccine and 279 days later he developed hib meningitis which was confirmed by a spinal tap.
VAERS ID 324934
A 15 week old boy DIED after having his vaccinations on 15th July 2008.
Information regarding PREVNAR was received from a pediatrician regarding a 15-week-old male patient who experienced Pneumococcal meningitis. At 15 weeks of age, the patient received the first dose on 15-Jul-2008. He also received the first doses of HIB (manufacturer unknown), Poliomyelitis Vaccine Inactivated (manufacturer unknown), DTaP and ROTATEQ (Merck & Co Inc) on 15-Jul-2008. Relevant medical history was not provided. Concomitant therapy included Hepatitis B Vaccine, HIB, ROTATEQ, DTaP and Poliomyelitis Vaccine Inactivated. On 25-Aug-2008, the patient presented with nystagmus, irritability and fever. He was hospitalized and diagnostic tests were performed (see test results), however serotyping was not performed. The blood culture and cerebral spinal fluid culture were positive for Pneumococcus. The patient was diagnosed as having Pneumococcal meningitis drug ineffective on 25-Aug-2008. Treatments were not reported. The patient died on 28-Aug-2008. The physician considered PREVNAR to be ineffective in preventing Pneumococcal meningitis, but stated that she realized that only receiving one dose in the series did not confer immunity to the disease. No further information was available at the time of this report. The cause of death was reported as meningitis Pneumococcal.
VAERS ID 325003
A 2 month old girl was vaccinated with DTAPHE HIB PNC ROTHB5. Unresponsive after vaccinations and developed a fever.
2 days later she was diagnosed with meningitis.
She had been previously healthy with no pre-existing conditions.
The VAERS reports were only an example of the 33 pages of meningitis after hib vaccine reports that I studied and these are only the cases which were notified by doctors in the USA
Prevnar Vaccine Is Causing Superbug Ear Infections
A vaccine that has dramatically curbed pneumonia and other serious illnesses in children is having an unfortunate effect: promoting new superbugs that cause ear infections.
On Monday, doctors reported discovering the first such germ that is resistant to all drugs approved to treat childhood ear infections. Nine toddlers in Rochester, N.Y., have had the germ and researchers say it may be turning up elsewhere, too.
Prevnar prevents seven strains responsible for most cases of pneumonia, meningitis and deadly bloodstream infections. But dozens more strep strains exist, and some have flourished and become impervious to antibiotics since the vaccine combats the more common strains.
If the new strains continue to spread, "it tells us the vaccine is becoming less effective" and needs to be revised, said Dr. Dennis Maki, infectious diseases chief at the University of Wisconsin-Madison Hospitals and Clinics.
Wyeth anticipated this and is testing a second-generation vaccine. But it is at least two years from reaching the market, and the new strains could become a public health problem in the meantime if they spread hard-to-treat infections through day-care centers and schools.
"I don't think the new strains are moving fast enough to call it a race, but the fact is that certain strains are increasing," said Peter Paradiso, a scientist at Wyeth Vaccines, the Collegeville, Pa., division that makes Prevnar.
"It is very worrying," said Dr. Keith Klugman, an infectious diseases specialist at Emory University. "With the eradication of all the other types in the vaccine, this one is emerging."
Several research teams reported on the situation Monday at microbiologists meeting.
Associated Press 17th September 2007.
Oral Rotavirus Vaccine Linked To a Significant Increase In Pneumonia Deaths In Children
US officials released a report on Friday which examined the findings of 11 trials of a new oral rotavirus vaccine from GlaxoSmithKline. The report stated that the vaccine was effective at preventing rotavirus infection. Unfortunately, it was also linked to a significant increase in pneumonia deaths in children, as well as an increase in convulsions and bronchitis.
Rotavirus is one of the most common causes of severe diarrhea in children, resulting in 55,000 hospitalizations for dehydration in the US each year. This isnt the first time there has been a problem with a vaccine against rotavirus. In 1999, a rotavirus vaccine made by Wyeth was pulled off the market because it was associated with intussusception, a condition where one portion of the intestine telescopes into a nearby portion, causing an intestinal blockage. Analysis of the studies on Rotarix showed no association between the new vaccine and this serious intestinal complication.
If youre worried that your baby may have received this vaccine, dont panic. There is a different oral rotavirus vaccine on the market in the US called RotaTeq, which is made by Merck, and has been FDA approved since February 3, 2006. Ironically, that happens to be the same week my own daughter was discharged from the NICU, where her stay was extended by serious complications from a rotavirus infection. Originally, I was angry that we missed out getting the vaccine by such a narrow window, but then cases of intussusception began cropping up in infants who received the vaccine after the trial.
The Food and Drug Administration advisory meeting is scheduled to discuss the possible approval of GlaxoSmithKline Plcs new rotavirus vaccine, Rotarix, on Wednesday, February 20th. Hopefully they will decide that in the case of Rotarix, the benefits do not outweigh the risks, at least in places where rehydration in a hospital setting is usually feasible.
By Dr. Kristie McNealy.
Prevnar Vaccine Does Not Prevent Ear Infections As Some Medics Claim
Pneumococcal conjugate vaccine prevents recurrent acute otitis media (AOM) in infants immunised at 2, 4, 6, and 1215 months of age. We aimed to find out whether this vaccine also prevents AOM in older children who have had previous episodes of AOM.
We noted no reduction of AOM episodes in the pneumococcal vaccine group compared with controls (intention-to-treat analysis: rate ratio 1·25, 95% CI 0·991·57). Although nasopharyngeal carriage of pneumococci of serotypes included in the conjugate-vaccine was greatly reduced after pneumococcal vaccinations, immediate and complete replacement by non-vaccine pneumococcal serotypes took place.
These data do not lend support to the use of pneumococcal conjugate vaccine to prevent otitis media in previously unvaccinated toddlers and children with a history of recurrent AOM.
The Lancet, Volume 361, Issue 9376, Pages 2189 - 2195, 28 June 2003.
VAN UK'S Comment: I think ear infections are largely an illness of the vaccinated and bottle fed. My eldest daughter was bottle fed after an episiotomy that went wrong and debilitated me so much I couldn't care for her. She had 2 ear infections.
My other 4 children who are unvaccinated but all had breast milk have not had one ear infection between them in 11 years since I gave birth to my second child. I don't believe this is a coincidence.
MMR DOESN'T WORK
Subclinical Measles Occured In 45% of Vaccinated Children Exposed To Measles
'Subclinical measles occurred in 45 percent of vaccinated children exposed to natural measles. "new epidemics, albeit milder in form, may occur in vaccinated areas[, a fact] which should be recognised in campaigns to eradicate measles."
The Lancet, vol. 353, January 9, 1999, pp. 98-102.
A History Of Prior Vaccination Is Not Always Associated With Immunity
30 measles sufferer's WITH detectable anti-bodies to measles were studied.
17 of these cases had been previously vaccinated against measles.
Clin. Invest. Med., vol. 11, no. 4, August 1988, pp. 304-9.
Measles outbreak in a fully immunized secondary-school population
An outbreak of measles occurred among adolescents in Corpus Christi, Texas, in the spring of 1985, even though vaccination requirements for school attendance had been thoroughly enforced. Serum samples from 1806 students at two secondary schools were obtained eight days after the onset of the first case. Only 4.1 percent of these students (74 of 1806) lacked detectable antibody to measles according to enzyme-linked immunosorbent assay, and more than 99 percent had records of vaccination with live measles vaccine. Stratified analysis showed that the number of doses of vaccine received was the most important predictor of antibody response. Ninety-five percent confidence intervals of seronegative rates were 0 to 3.3 percent for students who had received two prior doses of vaccine, as compared with 3.6 to 6.8 percent for students who had received only a single dose. After the survey, none of the 1732 seropositive students contracted measles. Fourteen of 74 seronegative students, all of whom had been vaccinated, contracted measles. In addition, three seronegative students seroconverted without experiencing any symptoms. We conclude that outbreaks of measles can occur in secondary schools, even when more than 99 percent of the students have been vaccinated and more than 95 percent are immune.
N Engl J Med 1987 Mar 26;316(13):771-4.
80% Of Children With Measles Had Been Vaccinated
Cases of measles among 165 vaccinated and unvaccinated children were studied and the level of measles antibody in 230 previously vaccinated children was determined. Associations between demographic factors and immunological response to vaccination were also investigated. Approximately 80% of the children with measles had been vaccinated; their cases had significantly lower rates of complication.
East Mediterr Health J. 1998 Dec;4(3):437-47. [MEDLINE record in process] PMID: 10415952; UI: 99344441.
MMR mass vaccination has not interrupted the circulation of rubella virus in Switzerland
n evaluating the impact of the MMR mass vaccination program begun in Switzerland in 1985, "we conclude that MMR mass vaccination has not interrupted the circulation of rubella virus in Switzerland, and that improvements in the implementation and surveillance of the MMR vaccination campaign are necessary in order to avoid [the] untoward effects of it."
(European Journal of Epidemiology, vol. 11, no. 3, June 1995, pp. 305-10).
Iowa Mumps Epidemic Puzzles Officials - of 245 cases 66% had recieved two doses of vaccine and 14% had recieved one dose of vaccine.
As of Thursday, 245 confirmed, probable or suspected cases of mumps had been reported to the Iowa Department of Public Health since mid-January. The federal Centers for Disease Control and Prevention said it is the only major outbreak in the nation.
We are calling this an epidemic, not just an outbreak, said Iowa state epidemiologist Dr. Patricia Quinlisk, explaining that mumps has spread to more than one-third of the state and does not appear to be confined to certain age groups or other sectors of the population.
A mumps vaccine was introduced in 1967. Iowa law requires schoolchildren to be vaccinated, and the states last major outbreak was in 1987, when 476 people were infected.
Of the 245 patients this year, at least 66 percent had had the recommended two-shot vaccination, while 14 percent had received one dose, the Public Health Department said.
The vaccine is working, Quinlisk said. The vaccine certainly was made to cover this particular strain, because its a fairly common strain of mumps. Quinlisk said the vaccine overall is considered about 95 percent effective.
Quinlisk said the mumps started in eastern Iowa and is spreading statewide and possibly into the neighboring states of Illinois, Minnesota and Nebraska. Those states may have one or two cases of the mumps, she said.
When 11-year-old Will Hean of Davenport starting feeling sick in mid-January, his family thought he had a bad case of the flu. But his face and throat swelled and his temperature climbed to 103. His parents took him to the doctor, and he was diagnosed to their surprise with full-blown mumps.
The Associated Press. MSNBC.msn.com. 31st March 2006.
Measles Attack Rate Was Much Higher In Vaccinated Than Unvaccinated Children
Cherry et al. (1972) described an epidemic in St Loius Cityand County during 1970 & 1971, during which 130 children were hospitalised and 6 died. The attack rate was much higher in vaccinated than unvaccinated children.
J Pediatr 1973 May;82(5):802-8
Encephalitis After Administration of Live Single Measles Vaccine - Measles Isn't The Only Thing That Can Cause Encephalitis - The Vaccine Can Cause It Too!
In a previously well child with no evidence of pre-existing immunologic defect a fatal encephalitis developed 10 days after administration of measles vaccine. There was pathologic evidence of an early viral encephalitis characterized by perivascular mononulcear infiltrates. Although the virus was not recovered, the diagnosis of a measles virus infection and encephalitis is supported by the postmortem findings of Warthin-Finkeldey cells in lymphoid tissues, an intranuclear inclusion in the brain and histologic changes of encephalitis.
Can Med Assoc J > v.112(8); Apr 19, 1975.
Measles inclusion-body encephalitis caused by the vaccine strain of measles virus - Measles Virus Found In Vaccinated Baby's Brain
We report a case of measles inclusion-body encephalitis (MIBE) occurring in an apparently healthy 21-month-old boy 8.5 months after measles-mumps-rubella vaccination. He had no prior evidence of immune deficiency and no history of measles exposure or clinical disease. During hospitalization, a primary immunodeficiency characterized by a profoundly depressed CD8 cell count and dysgammaglobulinemia was demonstrated. A brain biopsy revealed histopathologic features consistent with MIBE, and measles antigens were detected by immunohistochemical staining. Electron microscopy revealed inclusions characteristic of paramyxovirus nucleocapsids within neurons, oligodendroglia, and astrocytes. The presence of measles virus in the brain tissue was confirmed by reverse transcription polymerase chain reaction. The nucleotide sequence in the nucleoprotein and fusion gene regions was identical to that of the Moraten and Schwarz vaccine strains; the fusion gene differed from known genotype A wild-type viruses.
Revue / Journal Title
Clinical infectious diseases ISSN 1058-4838 CODEN CIDIEL
Source / Source
1999 Annual IDSA Meeting (1999)
1999, vol. 29, no 4, pp. 960-1112 (52 ref.), pp. 855-861.
Due to Vaccination Measles Now Affects Adults When It Is More Serious - 58% of Vaccinated People Had One Or More Symptoms Of Measles
An outbreak of measles at the University of California at Los Angeles provided the opportunity to study clinical, epidemiologic, and serologic characteristics of the disease in young adults in the present vaccine era. Of the 34 cases studied, 18 occurred in persons who thought they were immune. Fifteen of 19 seronegative students vaccinated during the epidemic responded with a secondary (IgG) antibody response. Antibody prevalence studies indicated that 91% of the student population had measles antibody at the onset of the outbreak, and history relating to measles correlated poorly with antibody prevalence. Of 212 adults vaccinated, 58% complained of one or more symptoms. Seventeen percent were confined to bed, and in three women vaccine-associated illness was notably severe. That measles will continue to be a problem in adults with our present national approach to immunization is predicted.
Ann Intern Med. 1979 Jun;90(6):873-6. PMID: 443682; UI: 79185850.
VAERS Reports of death after MMR and other vaccines
VAERS ID 291678
An 18 month old boy was vaccinated with DTAP flu MMR and varicella (chickenpox) vaccine on 24th September 2007. The next day he died.
'Healthy 18 mo male with history of febrile seizure in 3/07 given MMR II, VZV, DTaP & Flu vaccine on 9/24/07. Child discovered by mother deceased in bed approx 9/25/07.'
Despite the fact that the child was healthy with no medical history other than febrile seizure his death was marked as 'pulmonary congestion' and 'unresponsive to stimuli' rather than vaccine death.
VAERS ID 297178
A 2 year old girl was vaccinated with DTAP HIB IPV MMR PNC and varicella.
She began a very high fever after vaccination and then died 3 days later.
She was born prematurely but had no complications after birth and no pre-existing conditions.
VAERS ID 248538
1 year old boy was vaccinated with MMR Varicella and flu vaccines on 22nd November 2005.
Patient became ill within 24 hours of vaccine administration with URI symptoms, He was then discovered by parents to have stopped breathing.
Mumps Virus Found In Baby's Bronchial Tract
VAERS ID 255329
A 13 month old girl who was taking inhaled cortosteroids was vaccinated with MMR and varicella vaccines on 1st April 2006.
Concomitant vaccine administered on the same day included a doe of measles mumps rubella vaccine. Concomitant therapy included an inhaled corticosteroid unspecified. On 4/9/2006 the patient was diagnosed with adenosine deaminase deficiency and the mumps virus had been isolated from her bronchial tract. The patient was hospitalized and died 16 days later.
VAN UK'S COMMENT: Taking cortosteroids are a contraindication as listed in the Merck Manual.
VAERS ID 257684
A 1 year old girl with an ear infection and a history of wheezing was vaccinated with DTAP HIB IPV MMR PNC and varicella vaccines on 31st May 2006.
She was given antibiotics for the ear infection at the same time as the vaccines.
Her mother phoned the doctor the following day to report her child had a fever and was not acting right and she was given 'standard post-immunization advice'. During the night she started having seizures and respiratory difficulties with her pulse dropping. Her mother drove her to the ER. Patient died shortly after arrival at hospital.
VAN UK'S COMMENT: Children should never be vaccinated when ill or on antibiotics as their immune systems are already stressed. Vaccines also contain antibiotics so she would have got more than one dose of those in addition to the 10 vaccines in one session that she was given.
VAERS ID 264460
A 4 year old girl was vaccinated with MMR in 2002 and suddenly died right after the vaccine was given. The event was immediately life threatening.
VAERS ID 302699
A baby boy was vaccinated with MMR while he had a fever and history of febrile seizures.
10 days later his mother found him dead in his cot.
Several infections were found in his lungs.
A Large Proportion Of Children Vaccinated With MMR Do Not Have Detectable Antibodies After 5-6 Years
The levels of antibody against measles, mumps, and rubella were determined at 56 years postimmunization in 468 children vaccinated with two different trivalent vaccines. The proportions of children without detectable antibody levels were 12 and 3.6% for measles (p<0.001), 14.9 and 7% for mumps (p=0.006), and 3.3 and 3.1% for rubella (p=0.88), respectively, in MMR® II and Trivirix® recipients. A higher proportion of those vaccinated at younger ages had undetectable or low levels of measles antibody. These data indicate that a large proportion of children vaccinated under routine conditions do not have detectable measles and mumps antibody.
Source: Elesvier Science LTD,
Volume 13, Issue 16, 1995, Pages 1611-1616.
Varicella developed in 25 of 88 children (28.4 percent) between
December 1, 2000, and January 11, 2001. The index case occurred in a
healthy child who had been vaccinated three years previously and who infected
more than 50 percent of his classmates who had no history of varicella. The
effectiveness of the vaccine was 44.0 percent (95 percent confidence
interval, 6.9 to 66.3 percent) against disease of any severity and 86.0
percent (95 percent confidence interval, 38.7 to 96.8 percent) against
moderate or severe disease. Children who had been vaccinated three years
or more before the outbreak were at greater risk for vaccine failure than
those who had been vaccinated more recently (relative risk, 2.6 [95 percent
confidence interval, 1.3 to 5.3]).
Conclusions In this outbreak, vaccination provided poor protection against varicella, although there was good protection against moderate or severe disease. A longer interval since vaccination was associated with an increased risk of vaccine failure. Breakthrough infections in vaccinated, healthy persons can be as infectious as varicella in unvaccinated persons.
Outbreak of Varicella at a Day-Care Center despite Vaccination
Karin Galil, M.D., M.P.H., Brent Lee, M.D., M.P.H., Tara Strine, M.P.H.,
Claire Carraher, R.N., Andrew L. Baughman, Ph.D., M.P.H., Melinda Eaton,
D.V.M., Jose Montero, M.D., and Jane Seward, M.B., B.S., M.P.H.
According to University of Maryland Medical Center, Chickenpox outbreaks are occuring in the vaccinated
Experts pushed for the new second-dose policy due to a number of recent chickenpox outbreaks among previously vaccinated schoolchildren.
A 2007 study in the New England Journal of Medicine also found that one dose of the vaccine may not be enough to provide complete immunity. Among 350,000 patients researchers studied over 10 years, 11,356 were reported to have chickenpox. A total of 1,080 of the patients had breakthrough disease, a modified form of chickenpox with a mild rash that can occur in some vaccinated people. According to the study, those most at risk were children ages 8 - 12 years who had been vaccinated at least 5 years before their current chickenpox infection.
They also state:
Side Effects of the Varicella (Chickenpox) Vaccine
* Discomfort at the Injection Site. About 20% of vaccine recipients have pain, swelling, or redness at the injection site.
* Severe Side Effects. Only about 5% of adverse reactions are serious. Such events include seizures, pneumonia, anaphylactic reaction, encephalitis, Stevens-Johnsons syndrome, neuropathy, herpes zoster, and blood abnormalities.
* Risk of Transmission. The vaccine may produce a mild rash within about a month of the vaccination, which can transmit chickenpox to others. Individuals who have recently been vaccinated should avoid close contact with anyone who might be susceptible to severe complications from chickenpox until the risk for a rash passes.
* Later Infection. Months or even years after the vaccination, some people develop a mild infection termed modified varicella-like syndrome (MVLS). The condition appears to be less contagious and has fewer complications than naturally acquired chickenpox.
Transmission of varicella-vaccine virus from a healthy 12-month-old child to his pregnant mother. She had an abortion and the baby turned out to be unaffected. Total waste of human life.
A 12-month-old healthy boy had approximately 30 vesicular skin lesions 24 days after receiving varicella vaccine. Sixteen days later his pregnant mother had 100 lesions. Varicella-vaccine virus was identified by polymerase chain reaction in the vesicular lesions of the mother. After an elective abortion, no virus was detected in the fetal tissue. This case documents transmission of varicella-vaccine virus from a healthy 12-month-old infant to his pregnant mother.
J Pediatr 1997 Jul;131(1 Pt 1):151-4 Department of Pediatrics, University of California, Los Angeles School of Medicine, USA.
VAERS Reports Of Chickenpox After Varicella Vaccine - It Isn't Always Milder In The Vaccinated!
VAERS ID 74810
A 6 year old boy was vaccinated with varicella vaccine and he developed varicella 13 days after the vaccine, which then developed into pneumonia.
VAERS ID 75212
A 3 year old girl was vaccinated with varicella vaccine and 8 days later she got varicella.
pt recv vax; rash noted 8 days p/ vax, greater than 50 varicella eruptions over trunk, face;low grade fever; very cranky; fever 102.
VAERS ID 75754
A 6 year old boy was vaccinated with varicella vaccine and 13 days later he got varicella.
devel varicella and pneumonia; pt's hospitalization was prolonged;pt's MD felt pt may have aspiration pneumonia.
He had numerous pre-existing conditions that should have contraindicated vaccination.
VAERS ID 308573
Two siblings BOTH DIED after varicella vaccine.
It was reported in a published article that a patient was vaccinated with a dose of VARIVAX (Oka/Merck). After vaccination, the patient died two months after receiving a diagnosis of familial hemophagocytic lymphohistioicytosis. An autopsy was not performed. It was reported that the patient's older sibling died after vaccination with VARIVAX (Oka/Merck) (WAES # 0803USA04484).
Younger age at vaccination may increase risk of varicella vaccine failure. Despite varicella vaccination coverage of 80%, a sizeable outbreak occurred
To determine vaccine effectiveness (VE), a varicella outbreak in a highly vaccinated day-care center (DCC) population in Pennsylvania was investigated. In Pennsylvania, proof of immunity is required for children >or=12 months old for DCC enrollment. Questionnaires were administered to parents of children who had attended the DCC continuously during the study period (1 November 1999-9 April 2000) to determine history of varicella disease or vaccination and for information about any recent rash illnesses. VE was calculated for children >or=12 months old without a history of varicella. There were 41 cases of varicella among 131 attendees, with 14 cases (34%) among vaccinated children. VE was 79% against all varicella and 95% against moderate or severe varicella. Vaccination at <14 months was associated with an increased risk of breakthrough disease (relative risk, 3.0; 95% confidence interval, 0.9-9.9). Despite varicella vaccination coverage of 80%, a sizeable outbreak occurred. Early age at vaccination may increase the risk of vaccine failure.
J Infect Dis 2002 Jul 1;186(1):102-5.
Hepatitis B - No Significant Decrease In Hep B Despite Vaccination
Testing of participants in 2 national surveys demonstrates no significant decrease in hepatitis B virus infection, despite the availability of hepatitis B vaccine.
Source: AM J Public Health. 1999;89:14-18.
VAN UK's Comment: Hepatitis B is a sexually transmitted disease. It CANNOT be caught by newborn babies unless the mother has the disease, which most mothers don't. Despite this, all babies in the US and Ireland are routinely vaccinated
Gardasil Vaccine Against Cervical Cancer And Genital Warts Has Caused Genital Warts in 78 People Including 3 Primary Age Children
Gardasil Has Caused 78 cases of Genital Warts Including 3 in School Children
Earlier this year the Watchdog Judicial Watch reported that from information they obtained from the FDA under the freedom of information act - there have been 9749 adverse reactions to Gardasil vaccine and 21 deaths.
Also reported were 27 life threatening cases and 10 miscarriages. There have also been 78 cases of genital warts including 3 cases in primary aged children.
In Fiji, Ragogo writes, Effectively, Cabinet approved a vaccine which is still being tested so no one can be sure of its effectiveness or long-term side effects. Our children are guinea pigs for a money-making, I mean, drug-making, machine.
In a television interview with CBS News in May, Dr. Diane Harper, the specialist who helped develop the Gardasil vaccine, said making the vaccination mandatory is a real danger zone.
The vaccine has not been out long enough for us to have post-marketing surveillance to really understand what all of the potential side effects are going to be, Harper said. To put in place a process that says you must have this vaccine means that you must be part of a big public experiment and so we can't do that. We can't have that until we have more data.
Source: LifeSiteNews.com 18 November 2008.
TB Vaccines Could Spread Infection
TB vaccinations could actually spread the lung infection by clearing the way for tougher strains to flourish, a new study has claimed.
Vaccinating against tuberculosis might simply remove a weak form of the infection, allowing a virulent strain to break out, researchers from the University of Bristol found.
Nearly nine million new cases of TB break out every year, with nearly two million deaths worldwide. Efforts to create a vaccine have created more than 200 candidates, many of which are currently undergoing animal testing and early clinical trials.
Large-scale genetic analysis of strains of TB mycobacteria have shown they are more varied than first thought and that vaccines may be effective against only some of the circulating strains.
Dr Caroline Colijn, from Bristol's department of engineering and maths, devised several models to replicate how these various strains would react to certain drugs.
She said: "In most scenarios increasing vaccine coverage reduces the overall TB burden. However, the benefits are reduced if the preferential removal of one strain allows a previously suppressed strain to succeed.
"We found that there is a possibility that TB prevalence may increase due to a vaccination programme effective against a dominant strain, if that strain didn't provoke a good immune response."
Source: Nursing In Practice, 10th October 2008.
Two Boys Die of Rabies After FOUR Rabies Vaccinations
A major investigation is under way following the deaths of two boys who received rabies inoculations in Guandong Province.
Both deaths occurred less than two weeks apart in Guangdong's Wengyuan County, and now the food and drug administration is looking into the batch of the vaccine concerned.
Zhong Yuwang died of rabies on June 28 after being bitten by a dog on his left hand and foot. He had received a month long course of four injections against the disease, but instead of speeding his recovery, the drug seemed to make him weaker, officials said.
A few days after Zhong's death, another boy died of the same symptoms after he had received the same treatment at the same clinic.
Initial investigations indicate that improper storage of the vaccine during transportation somehow affected the vaccine, making it ineffective in fighting against the disease, said He Jingquan, a director with the provincial food and drug administration.
He said the vaccine was not kept refrigerated during its two-hour journey from a drug wholesaler in Shaoguan to the family planning service centre in Wengyuan, where the boys received their injections.
Source: China Daily, 16th July 2005.
Boy Dies of Acute Rabies Encephalitis Despite Being Given NINE Rabies Vaccinations
Identification of the Negri bodies in the brain of an 8-year-old boy who died 8 days after a paralytic illness and 20 days after a dog bite, and who had received 9 injections of Semple's anti-rabies vaccine, provided evidence that he died of acute rabies encephalitis and not of post-vaccinal allergic encephalomyelitis. The Negri bodies in the human subject and those seen in the inoculated mouse differed in their morphological structure: the former consisted of a matrix of very fine granular material bearing larger granules or strands of higher electron-density resembling nucleic acids and representing products of host cell-virus interaction; and the latter showed better defined areas of granular matrix containing tubular, bullet-shaped and elongated forms of viral structures, and nucleocapsids or capsule-deficient cores, representing the virions, emerging from them. Fine structural examination of the patient's brain and of the inoculated mouse has provided evidence of the pleomorphism of the Negri bodies and the various stages of formation of viral material and virions in them, the animal alone showing the mature virions of rabies, and proving the infectivity of the Negri bodies of the human brain.
Source: J Neurol Sci. 1986 Sep;75(2):181-93. PMID: 3760910; UI: 87010723.
Eczema Vaccinatum From His Smallpox Vaccinated Dad
On March 3, 2007, a 2-year-old boy was hospitalized with eczema vaccinatum. His two siblings, one with eczema, were subsequently removed from the home. Swabs of household items obtained on March 13th were analyzed for orthopoxvirus DNA signatures with real-time PCR. Virus culture was attempted on positive specimens. Eight of 25 household samples were positive by PCR for orthopoxvirus; of these, three yielded viable vaccinia virus in culture. Both siblings were found to have serologic evidence of orthopoxvirus exposure. These findings have implications for smallpox preparedness, especially in situations where some household members are not candidates for vaccination.
Source: Vaccine, Volume 27, Issue 3, 14 January 2009, Pages 375-377 - we're not at that date yet but I guess this will be the publication date of the journal.
VAN UK'S Comment: 'Vacca' means cow and vaccinia is the virus from cowpox which was used to formulate smallpox vaccine. Cases of eczema vaccinatum can be seen on the CDC Vaccine Damage page.
Sometimes vaccinia is also used to describe severe infection following vaccination in which the person suffers from gangrene.
Vaccines Cause 'Enhancement' of Viruses
Examples of vaccine-induced enhancement of susceptibility to virus infection or of aberrant viral pathogenesis have been documented for infections by members of different virus families. Several mechanisms, many of which still are poorly understood, are at the basis of this phenomenon. Vaccine development for lentivirus infections in general, and for HIV/AIDS in particular, has been little successful. Certain experimental lentiviral vaccines even proved to be counterproductive: they rendered vaccinated subjects more susceptible to infection rather than protecting them. For vaccine-induced enhanced susceptibility to infection with certain viruses like feline coronavirus, Dengue virus, and feline immunodeficiency virus, it has been shown that antibody-dependent enhancement (ADE) plays an important role. Other mechanisms may, either in the absence of or in combination with ADE, be involved. Consequently, vaccine-induced enhancement has been a major stumble block in the development of certain flavi-, corona-, paramyxo-, and lentivirus vaccines.
Also recent failures in the development of a vaccine against HIV may at least in part be attributed to induction of enhanced susceptibility to infection (i.e. vaccines against HIV caused HIV - VAN'S emphasis).
There may well be a delicate balance between the induction of protective immunity on the one hand and the induction of enhanced susceptibility on the other. The present paper reviews the currently known mechanisms of vaccine-induced enhancement of susceptibility to virus infection or of aberrant viral pathogenesis.
Volume 27, Issue 4, 22 January 2009, Pages 505-512 .
Acute Hepatitis B In A Vaccinated Healthcare Worker Who Had Received FIVE Hep B Vaccines!
CASE REPORT: Here, we describe an acute hepatitis B infection in a patient who received five hepatitis B vaccinations. Although his initial response to vaccination was moderate, he finally reached an excellent hepatitis B surface antibody level (anti-HBs) titres of more than 1000 IU/l in response to a booster vaccination with a recombinant DNA vaccine. Nevertheless, he developed full-blown acute hepatitis due to an HBV infection 14years after this booster vaccination. A DNA analysis of the surface protein encoding region followed by phylogenetic analysis showed that our patient was infected with a normal HBV strain that is circulating among men who have sex with men. To our knowledge, this is the first report of a genuine hepatitis B vaccination failure in someone who acquired a high anti-HBs level in response to a recombinant DNA hepatitis B vaccine. CONCLUSION: Healthcare workers whose response to the initial hepatitis B vaccination is moderate might be vulnerable to hepatitis B virus infection.
Source: J Hepatol. 2008 Dec 6.
Introduction of NEW TYPE of pneumonia following introduction of Prevnar vaccine
The nasopharyngeal (NP) prevalence of the 6C serotype was determined using 1326 pneumococcal isolates collected from 7 cohorts of Massachusetts children between 1994 and 2007. Initially, the isolates were serotyped using the quellung reaction; subsequently, stored specimens of all putative 6A isolates were tested for 6C using monoclonal antibodies. The opsonophagocytic and antibiotic susceptibilities of the isolates were determined.
Conclusions. Among NP isolates, the prevalence of 6C isolates has increased and the prevalence of 6A isolates has decreased since the introduction of PCV7 in Massachusetts in 2000. The observed increase in serotype 6C prevalence may be explained by the induction by PCV7 of low amounts of functional anti-6C antibody, compared with anti-6A and anti-6B antibodies.
Put in plain English, a new type of pneumonia called 6C has occured and cases have been increasing since the introduction of Prevnar (PCV7).
Source: The Journal of Infectious Diseases 2009;199:320325.
Pneumococcal vaccine does not appear to protect against pneumonia
We included 22 trials involving 101 507 participants: 11 trials reported on presumptive pneumococcal pneumonia, 19 on all-cause pneumonia and 12 on all-cause mortality. The current 23-valent vaccine was used in 8 trials. The relative risk (RR) was 0.64 (95% confidence interval [CI] 0.430.96) for presumptive pneumococcal pneumonia and 0.73 (95% CI 0.560.94) for all-cause pneumonia. There was significant heterogeneity between the trials reporting on presumptive pneumonia (I2 = 74%, p < 0.001) and between those reporting on all-cause pneumonia (I2 = 90%, p < 0.001). The RR for all-cause mortality was 0.97 (95% CI 0.871.09), with moderate heterogeneity between trials (I2 = 44%, p = 0.053). Trial quality, especially regarding double blinding, explained a substantial proportion of the heterogeneity in the trials reporting on presumptive pneumonia and all-cause pneumonia. There was little evidence of vaccine protection in trials of higher methodologic quality (RR 1.20, 95% CI 0.751.92, for presumptive pneumonia; and 1.19, 95% CI 0.951.49, for all-cause pneumonia in double-blind trials; p for heterogeneity > 0.05). The results for all-cause mortality in double-blind trials were similar to those in all trials combined. There was little evidence of vaccine protection among elderly patients or adults with chronic illness in analyses of all trials (RR 1.04, 95% CI 0.781.38, for presumptive pneumococcal pneumonia; 0.89, 95% CI 0.691.14, for all-cause pneumonia; and 1.00, 95% CI 0.871.14, for all-cause mortality).
Interpretation: Pneumococcal vaccination does not appear to be effective in preventing pneumonia, even in populations for whom the vaccine is currently recommended.
Source: CMAJ January 6, 2009; 180 (1). doi:10.1503/cmaj.080734.
Mumps Despite Shots
In a study reported in last weeks New England Journal of Medicine, researchers from the Centers for Disease Control and Prevention and several Midwestern state health departments examined the 6,584 cases in the Midwestern outbreak. They found that the incidence was four times higher among people 18 to 24 years old than in all other age groups combined. This was despite the fact that 84% of the mumps patients in that age group (and 63% of the patients overall) had received the recommended two doses of mumps vaccine.
Close-contact living conditions, like on college campuses, helped spread the disease, says Jane Seward, the CDCs deputy director of the division of viral diseases and an author of the study. But it also appears that, in some vaccinated people, there was a decrease in immunity over time.
Source: The Los Angeles Times, Susan Brink, 14th April 2008.
Cases of Polio Rise After Vaccine Was Introduced - Even When Some Children Were Vaccinated 25 Times!
Four years ago, the government introduced a vaccine carrying P1, the deadliest strain of the virus.
But experts said, though most children have been repeatedly vaccinated, polio-related paralysis has been on the rise.
"Children are getting more than 25 doses. There are studies to show that in malnourished children, the vaccine can be fatal. It actually causes paralysis, so it is contraindicated in undernourished population," said Sathyamala, Epidemiologist.
The government's own data shows that in Uttar Pradesh, the cases of polio related paralysis rose from 3789 cases in 2004 to 10,055 after the P1 vaccine was introduced and six doses were given the next year.
The number had risen to 11,538 after children received nine doses.
Source: NDTV, 9th April 2008.
93% - 100% of Mumps Cases At 3 Universities Were Fully Vaccinated With Two Doses Of MMR
According to the meeting notes of the Advisory Committee on Immunization Practices, dated October 25th and 26th, 2006, three outbreaks of mumps at university campuses were in the vaccinated.
Between 93% and 100% had been given two doses of MMR.
Not only that, but the disease did NOT spread to the unvaccinated.
'Few infants, schools and daycare outbreaks have been reported with no spread to unvaccinated populations noted at this time.'
They asked the following questions in their meeting notes:
Is there a high number of mumps cases due to vaccine failure?
Would a THIRD dose of MMR be useful at preventing an outbreak?
Can mumps be eliminated using the current MMR vaccine?
The full meeting notes can be read at:
VAN UK'S Comment: If Two MMR vaccines didn't work, why would a third one?
12 CASES OF WHOOPING COUGH....ALL OF THE INFECTED CHILDREN HAD BEEN VACCINATED
A dozen cases of whooping cough have been found in children since the middle of last month in Hunterdon County, health officials said yesterday.
"It is not unusual to have individual cases. It is unusual for us to have this number of cases in this defined time period," said John Beckley, the Hunterdon County health director.
All of the infected children had been vaccinated, but Hunterdon officials said the immunity to the vaccine can wane between ages 7 and 9 and that there is no licensed vaccine for children in that age group.
Children should receive four doses of DTaP vaccine when they are between 2 months and 18 months old and an additional dose before starting school, the local health department said. The licensed Tdap pertussis booster for people ages 10 to 64, required for New Jersey school-aged children, might provide added protection, the department noted.
Louise Kuo Habakus, a member of the New Jersey Coalition for Vaccination Choice, said girls receive 69 shots by age 18 and boys get 66 during that time. "Our babies and our toddlers receive five pertussis shots until age 5, and that's not enough to protect them at age 7?" she said.
Source: The Star-Ledger, 15th January 2009.
3 DIE IN HOSPITAL OUTBREAK OF FLU - 2 WERE ALREADY VACCINATED
101 people at a hospital in Tokyo, Japan, caught flu from an infected healthcare worker who spread the virus to patients in seven of the hospital's eleven wards.
68 of the 77 inpatients who caught flu had been vaccinated, and 21 of the 24 healthcare workers who contracted it had been vaccinated.
There were 3 deaths - all women, aged 77, 85 and 100. Of the three who died, 2 had been vaccinated against flu.
Source: Kyodo News, 18th January 2009.
VAN UK'S Comment: I have noticed in my years of reading failure reports that the majority of cases and deaths appears to be in those who were vaccinated. Perhaps the vaccines didn't just 'fail' but rather caused some of the disease?
Maybe it weakened the immune system so the vaccinated person is less able to deal with the illness? If this were not the case, why are there not more cases and deaths in the unvaccinated?
Two Babies Got Meningitis....They Had Both Been Vaccinated
Two Calgary children are receiving hospital treatment for serious cases of the infection that can lead to meningitis, health authorities say.
Mersadiz Clark, 15 months, has been hospitalized since Tuesday, hooked up by tubes to machines to keep her alive, her father, Blake Clark said. Doctors have diagnosed his daughter with bacterial meningitis, he said.
"When we brought her in, she was limp like a sandbag, her head kept flopping to the side and her skin was yellow with red blotches all over," said the 22-year-old father.
The toddler's playmate, and cousin, Dayon, 4, is also at the children's hospital, he said.
Schnurr, 22, said her daughter has been diagnosed with bacterial meningitis, and is unsure how she contracted the infection. She was up-to-date on her vaccinations, Schnurr said, adding Dayon is being treated for the same infection and had also been vaccinated.
Source: Calgary Herald, 23 January 2009.
Outbreak Of Measles In Vaccinated Children In A Slum
Three cases of measles were admitted in Deptt. of Paediatrics, Govt. Medical College & Hospital, Chandigarh and were reported to the Deptt. of Community Medicine for an outbreak investigation. A trained team investigated the slum having a population of 25,000 and studied various features associated with epidemic between the period of April 22 to May 10, 2003. RESULTS: The study covered 484 houses having 1130 children. Among the children who developed measles 32.76% were vaccinated ones. In them attack rate was 3%. Attack rate in vaccinated children went on increasing as age increased. An overall attack rate of 5.13% (Peak incidence 6% in 1-4 years age group) was recorded. Among measles cases, one-fifth had post measles complications. As much as 32.76% children with measles had received measles vaccination in the past. Therefore something more than immunization by single dose of vaccine is required. Measles was reported to be higher amongst the children without Vitamin A supplementation (P<0.001). CONCLUSION: There is need to store vaccine properly and to strengthen routine immunization coverage, Vitamin A supplementation and health infrastructure in underprivileged population. Serological studies among vaccinated children against measles should be undertaken to explore the possibility of second dose of measles in older children.
Source: Indian Journal of Medical Sciences, 2004, vol.58, issue 2, p. 47-53.
VAN UK'S Comment: It's interesting they mention vitamin A and underprivileged populations. Measles complications can be caused by vitamin A deficiency and they can be prevented by the administration of vitamin A. Pity they never tell parents.
Mumps Outbreak - 15 out of 16 cases had been fully vaccinated with 2 doses of MMR
People are being urge to make sure they have had the MMR vaccination after 16 cases of mumps in Anglesey and Gwynedd in the last month.
The National Public Health Service for Wales (NPHS) says 15 of those affected have been given the recommended two doses of the MMR vaccine.
The health service said it is possible, but not common, to get mumps after being vaccinated with MMR which protects against measles, mumps and rubella and is given as part of the routine childhood immunisation programme.
Dr Hart added: "Anyone in a school or community where mumps cases are reported who have not already been fully immunised with two doses of MMR should be vaccinated immediately."
Source: BBC News, 24 January 2009.
VAN UK'S Comment: Why would people rush out to get an MMR jab when they've just admitted that 15 out of 16 were fully vaccinated? It seems totally nonsensical. Where are all the unvaccinated college students with mumps?
Why do there always seem to be more cases in the vaccinated?
Whooping Cough Confirmed - All Of The Kids Were 'Up To Date' On Their DTAP Vaccinations
The San Juan Basin Health Department has reported four more individuals have been confirmed as having pertussis (whooping cough) and two more cases are considered probable. These new cases are scattered throughout the county, including one case in a Bayfield preschool.
Nearly half of the cases diagnosed have occurred in the four-six year old age group. All of these kids are up to date on Dtap vaccination but had not yet received the kindergarten dose. If your child is nearing age 15 months of age or 4 years of age and has not had their booster dose of Dtap, we recommend vaccinating them as soon as possible because the protection from DtaP vaccine diminishes over time.
Source: Pine River Times, 23rd January 2009.
VAN UK's Comment: Children in the US get 4 doses of DTAP vaccine between the ages of 2 months and 18 months and another dose at 4 years old. The kid would have had their last vaccine only two or three years before and it still didn't work?
MENINGOCOCCAL DEATH RATE INCREASED 150% AFTER MENZB VACCINE
Ministry of Health data reveals the meningococcal disease case fatality rate has increased by 150 percent since the MeNZB vaccine was rolled out, resulting in 13 unexplained deaths.
Norway banned the vaccine because of safety concerns and refused to accept imports of it from France, yet the same vaccine is injected into healthy babies in New Zealand.
Source: Scoop Independent News, 13th November 2006, by Ron Law.
Differences in female-male mortality after high-titre measles vaccine and association with subsequent vaccination with diphtheria-tetanus-pertussis and inactivated poliovirus: reanalysis of West African studies
Females given high-titre measles vaccine (HTMV) have high mortality; diphtheria-tetanus-pertussis (DTP) vaccination might be associated with increased female mortality. We aimed to assess whether DTP or inactivated poliovirus (IPV) administered after HTMV was associated with increased female-male mortality ratio.
In three trials from West Africa, 2000 children were randomised to HTMV or control vaccine at 45 months of age; a second vaccination was given at age 910 months (standard measles vaccine). Children in high-titre groups were given IPV or DTP-IPV. Another 944 children received HTMV as routine vaccination in Senegal.
When we compared high-titre and control groups, no difference in mortality between the first and the second vaccination was noted. After the second vaccination, the female-male mortality ratio was 1·84 (95% CI 1·192·84) in children in the high-titre groups who received DTP-IPV or IPV, and 0·59 (0·341·04) in controls who received standard measles vaccine (p=0·007). Children who received HTMV but no additional DTP-IPV or IPV had a female-male mortality ratio of 0·83 (0·411·67). This ratio was 2·22 (1·044·71) for children who received DTP-IPV after routine HTMV and 1·00 (0·681·47) for those who did not. When we combined the results from all trials, the female-male mortality ratio was 1·93 (1·332·81) for those who received DTP or IPV after HTMV, and 0·96 (0·691·34) for those who did not (p=0·006).
A change in sequence of vaccinations, rather than HTMV itself, may have been the cause of increased female mortality in these trials.
Source: The Lancet, Volume 361, Issue 9376, Pages 2183 - 2188, 28 June 2003.
VAN UK'S Comment: Doctors repeatedly tell parents vaccines are safe and they don't cause death, yet this article specifically discusses the 'high mortality rate' after vaccination and shows doctors are fully aware of this. I'd call that murder.
Increased Mortality After Hepatitis B Vaccination
Because of the above findings that DPT and measles vaccine caused increased death in female children, they did a further study to see if Hep B vaccine would also cause increased death, and they found that it did:
Objective: Studies from high mortality areas have suggested that diphtheria-tetanus-pertussis may be associated with an increase in the mortality of girls relative to boys. We therefore examined whether hepatitis B vaccine (HBV) was associated with sex-specific differences in mortality.
Design: As part of a randomized trial of measles vaccine, a subcohort of 876 children was offered HBV at 7½, 9 and 10½ months of age. We examined whether this cohort differed in mortality rate and female-male mortality ratio compared with previous and subsequent birth cohort enrolled in the same trial.
Setting: Four districts in Bissau, the capital of Guinea-Bissau.
Subjects: Six annual birth cohorts of 8906 children registered in the study area and followed from 1½ to 12 months of age between March 1995 and February 2001. Of these children, 6399 took part in a 2-dose measles vaccination trial; of those born between March 1996 and February 1997, 876 received HBV.
Main Outcome Measures: (1) The mortality rate ratio (MR) between 7½ and 12 months and 1½ and 7½ months old children; (2) the female-male MR among trial children having received HBV plus measles vaccine or only measles vaccine.
Results: In cohorts not receiving HBV, the MR for children 7½-12 and 1½-7½ months of age was 0.97 95% confidence interval (95% CI), 0.79-1.24, whereas the MR was 1.62 (95% CI 1.09-2.41) in the cohort receiving HBV at 7½ months (test of homogeneity, P = 0.030). Among children enrolled in the measles vaccination trial, HBV-vaccinated children 7½-12 months of age had higher mortality than both prior and subsequent cohorts who had not received HBV (MR = 1.81; 95% CI 1.19-2.75), the difference being particularly strong for girls (MR=2.27; 95% CI 1.31-3.94). In the cohort who had received both HBV and measles vaccine, the female-male MR between 9 and 24 months of age was 2.20 (95% CI 1.07-4.54) compared with 0.96 (95% CI 0.70-1.32) in trial participants who had received measles vaccine only (test for homogeneity, P = 0.040). With longer follow-up, these tendencies remained the same.
Conclusions: These comparisons suggested changes in the mortality pattern after the introduction of HBV, particularly for girls. Hence in areas with high mortality, HBV may affect girls' and boys' susceptibility to infections differently.
Source: The Pediatric Infectious Disease Journal:Volume 23(12)December 2004pp 1086-1092.
13 Cases Of Whooping Cough In January In Kalamazoo
"We definitely have an outbreak going on," said Buzas, "we've had 35 cases between September and the end of December."
In fact, cases of pertussis have been steadily increasing for several years, and although there are some vague theories, no one is sure why.
"What we're seeing though is children who are immunized, completely immunized, are getting pertussis," said Buzas.
Source: WWMT.com news channel, 29 January 2009.
Update On Mumps Cases In Wales - Cases Have Risen From 13 To 21 And 18 Of The 21 Cases Are In The Vaccinated
THE number of people suffering from mumps in Anglesey and Gwynedd has risen to 21.
The majority of cases 18 are in young people who have already received two doses of the MMR vaccination, which protects against measles, mumps and rubella.
The National Public Health Service for Wales is urging people in the area to ensure they have had two doses of MMR.
Dr Judy Hart, a consultant in communicable disease control for the NPHS, said: The MMR vaccine is extremely effective in protecting against measles and rubella, with 99% of those who have received two doses protected for many years.
Source: WalesOnline, by Madelaine Brindley, 29 January 2009.
VAN UK'S Comment: They just said 18 of the 21 cases had TWO doses of MMR, yet they say it's so effective? The proof is right there that it isn't. Such good advertising for the jab!
10 Students Diagnosed With Chickenpox - 7 Had Been Vaccinated, 3 Had Not
Seven students at a Mira Mesa middle school and three children at a Santee child care center have been diagnosed with chicken pox, the San Diego County Health and Human Services Agency announced Friday.
None of the infected students at Challenger Middle School or the KinderCare Learning Center required hospitalization, according to the HHSA.
Five of the middle school students had one dose of vaccine; two had no vaccine. Two of the childcare children had one dose of vaccine, one had no vaccine.
Source: nbc San Diego Health, nbcsandiego.com, January 30th 2009.
Post-Vaccine Mumps Like Disease In Military Recruits In Italy
Italian military recruits have received mandatory mumps vaccination by Urabe Am9 strain since 1998. A previous study1 found that, in 1999, 37 episodes of mumps-like disease were found in recipients of the vaccine, and that 35 of these occurred within 1 month of immunization. To assess whether these cases were due to some expected residual virulence of the live attenuated Urabe Am9 mumps strain, we analyzed saliva samples from recruits who developed mumps-like disease within 1 month of vaccination.
Source: JAMA Vol. 287 No. 9, March 6, 2002.
Here's What Happens When You Vaccinate Babies Against Measles - Measles Epidemic Now Hits Adults 18-40 As Vaccine Wanes. Measles Is Serious In Adults And There Are 10 People In Critical Condition
The measles epidemic has occurred in several northern provinces, targeting adults aged 18-40 instead of children as usual, according to epidemiologists.
The disease can develop quickly and serious after-effects can include damage to cognitive functions, experts said.
The National Hospital for Infectious and Tropical Diseases is treating about ten measles patients, who are in comas, and listed as in a critical condition.
The number of measles patients has risen by 20 times to reach nearly 250 since the discovery of the first case two months ago. Ninety percent of them come from Hanoi.
The patients had initial symptoms such as light temperature and rashes which first began in the ears and then spread to their heads, faces and the soles of their feet.
The Central Epidemiology Institute and the National Hospital for Infectious and Tropical Diseases are actively working together to identify cases of infection and guide clinics in provinces and cities to fight the disease.
The best way to prevent measles is to get vaccinated now and once again in the next 20 years, said Dr Nguyen Van Kinh, head of the hospital.
Source: VOV News, 4th February 2009.
VAN UK'S Comment: or how about letting your child have measles when they're little and getting life-long immunity and protection from the severe complications of measles in adulthood?
21 Cases Of Whooping Cough, All Were Vaccinated As Vaccine Wanes At Age 7 To 9
As of this afternoon, the health department had 21 confirmed cases of whooping cough, known formally as pertussis. There also were five probable cases of the contagious disease, and a half-dozen possible cases are under investigation.
Of the first dozen cases of pertussis, 10 were children at the Clinton Public School and another was a child who came into contact with someone from the Clinton school.
The infected children had been vaccinated, but the immunity to the vaccine can wane between ages 7 and 9 and there is no licensed vaccine for children in that age group.
Source: The Star Ledger, 11 February 2009, by Mike Frassinelli.
Mumps Cases Rise By 50% In England And Wales - The Reason IS NOT Lack Of MMR
In January there were 265 cases of mumps in England and Wales, compared to 177 in the same month last year and 150 in January 2007.
Some have had one dose of the MMR jab but this has been shown not to offer full protection.
An epidemic of mumps struck the same group in 2005 when there were 43,000 cases. Since then cases of mumps have declined but remained higher than normal.
The rise is not due to low uptake rates of the MMR jab because the cases have not been seen in the younger age groups who should receive the vaccine.
Dr Mary Ramsay, who monitors mumps cases at the Health Protection Agency said: "The increased occurrence of the disease is mainly among older teenagers and young adults in their early twenties, and mostly among those in further or higher education establishments.
Source: The Telegraph, by Rebecca Smith, 13 March 2009.
VAN UK's Comment: These adults are getting mumps now, with a greater risk of mumps-meningitis, because they had the single measles shot as babies. If they had been allowed to get mumps as a child, they would not have this problem now.
Whooping Cough In Suffolk County, US. Those Affected Were Vaccinated
The county health commissioner says whooping cough is highly contagious and symptoms can develop anywhere from 3 days to 3 weeks, so parents need to be especially vigilant to help stop this from spreading countywide.
The warning comes after two students in the district have been diagnosed with the potentially fatal bacterial infection. The health department would only say they are elementary aged students and were being treated.
Chaudry said both students who contracted whooping cough had been immunized.
He suggested parents call their pediatricians about booster shots since it appears the vaccination is waning for an unknown reason. There are 70 to 80 cases every year in Suffolk County.
Source: WABC-TV, New York, 13 March 2009.
HIB Disease - New Strains Developing Because Of Advent Of Vaccine, Also Cases Of Regular HIB Are At The Same Rate As Before The Vaccine
In addition to the proportional increase in cases of non-type b Haemophilus influenzae disease in the post-H. influenzae type b vaccine era, the incidence of invasive H. influenzae disease was found to be approaching the rates of H. influenzae type b disease that were documented in the prevaccine period. Fifty-six percent of invasive disease now occurs in individuals aged >10 years.
Clin Infect Dis. 2007 Jun 15;44(12):1611-4. Epub 2007 May 2.
Overall Cases Of HIB Have INCREASED Since The Vaccine
We reviewed retrospectively all invasive Haemophilus influenzae (Hi) infections in adults ascertained from reference laboratory records and notifications from five NHS regions over the 5 years from 1 October 1990, a period encompassing the introduction of routine Hib childhood immunization (October 1992). A total of 446 cases were identified, a rate of 0.73 infections per 10(5) adults per annum. Though numbers of Hib infections in adults fell after the introduction of Hib vaccines for children (P = 0.035), and there was no increase in infections caused by other capsulated Hi serotypes, total numbers of invasive Hi infections increased due to a large rise in infections caused by non-capsulated Hi (ncHi) strains (P = 0.0067). There was an unexpectedly low rate of infections in those aged 75 years or more (P < 0.0001). The commonest clinical presentations were pneumonia with bacteraemia (227/350, 65%) and bacteraemia alone (62/350, 18%) and the highest rates of disease were in the 65-74 years age group (P < 0.0001). Clinical presentation was not influenced by the capsulation status of the invading Hi strain. 103/350 cases (29%) died within 1 month, and 207/350 (59%) within 6 months of their Hi infection. Case fatality rates were high in all age groups. Pre-existing diseases were noted in 220/350 cases and were associated with a higher case fatality rate (82% vs. 21%, P < 0.0001). After the introduction of Hib immunization in children, invasive Hib infections in unimmunized adults also declined, BUT THE OVERALL RATE OF INVASIVE HI DISEASE IN ADULTS INCREASED, with most infections now caused by non-capsulated strains. Physicians and microbiologists should be aware of the changing epidemiology, the high associated mortality and high risk of underlying disease. Invasive haemophilus infections in adults should be investigated and treated aggressively.
Source: Epidemiol Infect. 2000 Jun;124(3):441-7
443 Cases Of HIB Infection - 82% Of Cases Were Vaccinated. Vaccine Estimated To Only Be 56.7% 'Effective'.
In October 1992, Haemophilus influenzae type b (Hib) conjugate vaccine was introduced to infants in the United Kingdom with a "catch-up" program for those aged <4 years. Initially, the rate of invasive Hib disease decreased dramatically but has been increasing since 1999. To determine possible reasons for this increase, the effectiveness of Hib conjugate vaccine was estimated by use of the screening method. Between October 1993 and December 2001, a total of 443 cases of Hib infection occurred in children eligible for vaccination; 363 (82%) were fully vaccinated. Vaccine effectiveness was estimated to be 56.7% (95% confidence interval, 42.5-67.4). Effectiveness was lower in children vaccinated during infancy, compared with those who were vaccinated during the catch-up campaign (P=.0033), declined with time since vaccination (P=.0008), and was lower in children born during 2000-2002, compared with other children scheduled for infant vaccination (P=.0041). Use of a catch-up vaccination program enhanced the control of Hib infection in England and Wales. Since 1999, however, low effectiveness in infants, declining effectiveness with age, and the use of lower-efficacy vaccines have contributed to increased rates of Hib infection. The potential role of boosters needs to be considered.
Source: J Infect Dis. 2003 Aug 15;188(4):481-5. Epub 2003 Jul 31.
Haemophilus Influenzae A Increased 8 Fold After Vaccine For Haemophilus influenzae B
Surveillance for Haemophilus influenzae meningitis cases was performed in Salvador, Brazil, before and after introduction of H. influenzae type b (Hib) immunization. The incidence of Hib meningitis decreased 69% during the 1-year period after initiation of Hib immunization (from 2.62 to 0.81 cases/100,000 person-years; P<.001). In contrast, the incidence for H. influenzae type a meningitis increased 8-fold (from 0.02 to 0.16 cases/100,000 person-years; P=.008). Pulsed-field gel electrophoretic analysis demonstrated that H. influenzae type a isolates belonged to 2 clonally related groups, both of which were found before Hib immunization commenced. Therefore, Hib immunization contributed to an increased risk for H. influenzae type a meningitis through selection of circulating H. influenzae type a clones. The risk attributable to serotype replacement is small in comparison to the large reduction in Hib meningitis due to immunization. However, these findings highlight the need to maintain surveillance as the use of conjugate vaccines expands worldwide.
Source: J Infect Dis. 2003 Jan 1;187(1):109-16. Epub 2002 Dec 13.
VAN UK'S Comment: This is what happens with vaccination, a disease may go down but then another type of the disease sky rockets - its called serotype conversion or mutation
16 People Who Had Recieved 3 Or More Tetanus Vaccines, Still Got Tetanus
Sixteen (13%) of the 122 non-neonatal patients with supplemental data were reported to have received at least a primary series (i.e., three or more doses) of TT before onset of illness (Table_1), including two (40%) of the five non-neonatal patients aged less than 20 years. Three (60%) of the non-neonatal patients aged less than 20 years were unvaccinated because of their parents' religious objections. The fourth case occurred in a boy aged 14 years who was bitten by a dog and who had received his last dose 2 years previously. This patient did not seek medical care for his injury and was later hospitalized with tetanus for 2 days. He did not require mechanical ventilation and subsequently recovered. The fifth case occurred in a boy aged 15 years who was in a moped crash; the interval since his last dose was 11 years. The patient sought medical attention and received TT within 6 hours of his injury; he was hospitalized 4 days and recovered without sequelae.
Source: MMWR, July 03, 1998 / 47(SS-2);1-13,
Tetanus Surveillance -- United States, 1995-1997
Boy Catches Pneumonia After THREE Doses Of Prevnar And They Don't Think Antibodies Can Protect The Individual
We measured the concentration, opsonic activity, and avidity of serotype-specific serum antibodies in a pneumococcal conjugate vaccine (PnCRM7) efficacy trial participant who contracted serotype 14 pneumococcal bacteremia following dose 3 of PnCRM7. Controls included 18 PnCRM7- and 10 MnCC-vaccinated children without invasive pneumococcal disease (IPD). The child with vaccine failure had 4.98 mcg/mL of serotype 14 antibodies 10 days before disease onset; these antibodies had greater opsonic activity and lower avidity than those of control PnCRM7 recipients. The child had no booster response to a fourth dose of PnCRM7 for most vaccine serotypes. We conclude that antibody concentration, functional activity and avidity do not predict individual protection against IPD, and immunological correlates of protection are only useful at the population level.
Vaccine, Volume 27, Issue 12, 13 March 2009, Pages 1863-1868
Indian Babies Don't Need Hib Vaccine Because They Have Natural Immunity And Much Less Hib Than Western Children
The authors found the incidence of hib meningitis to be only 0.007% and they speculate that the population may have natural immunity to invasive hib disease.
In Asia, hib disease is very low, 6 in 100,000, compared with the 109 in 100,000 in the Western Pacific.
The study revealed a remarkably low incidence of hib disease, not convinced, WHO undertook a large population based study in Tamil Nadu, assuming that the previous hospital based study would miss cases of meningitis in the community, before they reach the hospital. The very low incidence of in this community based study is therefore of great interest to epidemiologists.
Unfortunately because of the delay in publication of the study, the data could not inform the debate prior to the decision of WHO to recommend Hib vaccination to all infants. We have previously suggested that natural immunity was the reason for the low incidence of hib disease in India and the reason why this population does not need vaccination with hib.'
Source: Indian J Med Res 129, February 2009, pp.205-207.
VAN UK's Comment: I think there is less hib in India because more women breast feed and for longer and breast milk has antibodies to hib in it, also they have lower rates of vaccination in India, which has been shown to cause hib
Whooping Cough Vaccine Not Working And New Strain Of Whooping Cough Emerging
Pertussis (whooping cough) is a potentially fatal respiratory disease caused by the bacterium Bordetella pertussis. Despite effective vaccination programs, there has been concern in some developed countries that pertussis cases are on the increase. We characterized 703 clinical B. pertussis isolates collected in the United Kingdom between 1920 and 2006 using multilocus variable-number tandem repeat analysis (MLVA), pertactin (prnA) and pertussis toxin (ptxA) genotyping, and serotyping. The results showed that the genetic diversity of the bacterial population decreased during periods of high vaccine coverage. However, it was elevated between 1977 and 1986, when vaccine coverage in the United Kingdom was low and epidemics occurred. A high proportion of MLVA types during this epidemic period were novel, and the prnA(2) and prnA(3) alleles were seen for the first time in the United Kingdom. MLVA-27 appeared in 1982, was codominant during the 1998-to-2001 period, and comprised ~70% of isolates during both the 2002-to-2004 and the 2005-to-2006 periods. The United Kingdom is dominated currently by an MLVA-27 prnA(2) ptxA(1) serotype Fim3 clonal type. Even during recent periods dominated by MLVA-27, many novel types were found at low frequencies, suggesting that either there are a large number of uncommon MLVA types circulating at low frequencies or new types are constantly arising. This supports a hypothesis that MLVA-27 is under some form of positive selection conferring increased survival in a highly vaccinated population.
Source: Journal of Clinical Microbiology, March 2009, p. 680-688, Vol. 47, No. 3.
Rotavirus Vaccine Caused Rotavirus Infection In Two Immune-Suppressed Babies
Two infants receiving the first two of three scheduled doses of the live, attenuated-virus rotavirus vaccine (RotaTeq) developed infections traced to the product, according to Niraj C. Patel, M.D., of Baylor College of Medicine in Houston.
After the babies were hospitalized with diarrhea and other symptoms consistent with rotavirus infection, it was discovered that they had severe combined immunodeficiency syndrome (SCID).
These are the first reported cases of infection caused by the rotavirus vaccine, which was approved in 2006, Dr. Patel said in a late-breaking research session here at the American Academy of Allergy, Asthma, and Immunology meeting.
Dr. Patel said molecular analyses showed that the vaccine caused the infections. All the attenuated virus strains used in the vaccine contain two bovine genes that aren't found in wild-type human rotavirus. Both were present in the rotavirus isolates obtained from the babies.
Source: Medpage Today, March 18 2009.
In Whooping Cough Epidemic, 17 out of 18 Cases Had Had FIVE Doses Of DTaP!
A cluster of whooping cough cases among Cobb County elementary students is adding to concerns that an important vaccine isnt as effective as it needs to be to stop the spread of disease.
Of the 18 students in the recent Cobb cluster, 17 were properly immunized with five doses of DTaP vaccine, which protects against diphtheria, tetanus and pertussis, health officials said.
Despite the fact that we routinely vaccinate against pertussis, pertussis is endemic. Theres lots of pertussis, said Dr. Nancy Messonnier, director of CDCs meningitis and vaccine preventable diseases branch.
East Cobb parent Laurie Wood assumed her children were protected because theyd received all the shots. Then her 8-year-old son, Charlie, developed a cough so severe it caused him to vomit. In January, Charlie was diagnosed with pertussis.
I was scared because hes been vaccinated, Wood said last week. I also was mad because if the vaccination wasnt working, we should have known about it.
To try to determine the magnitude of the problem at the four Cobb schools, last month CDC and local health officials gave voluntary pertussis tests to 108 children and staff who were currently coughing, and 22 of them showed evidence of recent infection, said Julie Gabel, a state health department epidemiologist.
Despite the studys test results, some doctors refused to believe parents when they said that their children had pertussis. More than one said to the parent: Well, your child couldnt have had pertussis, your childs been vaccinated, Gabel said, adding that the department is working to educate physicians.
Source: The Atlanta Journal-Constitution, by Alison Young, 22nd March 2009.
Man Paralysed By His Daughter's Polio Vaccine, Wins Compensation
A Staten Island man stricken with polio after changing his daughter's diaper 30 years ago won a multimillion dollar judgment from the maker of the oral vaccine that passed through her stool.
Dominick Tenuto, who fell ill while working at a small Wall Street securities firm in 1979, was awarded $22.5 million on Friday. The award is believed to be among the highest ever on Staten Island.
"It was a long legal fight and we finally prevailed," Tenuto, 61, told the Daily News Saturday. "We waited 30 years."
The jury determined that the Orimune vaccine his daughter, Diana, received was "unreasonably dangerous" and that drugmaker Lederle Laboratories was "100% liable" for his injuries. The jury also found that the company failed to warn doctors of the vaccine's potential risks.
Tenuto and his lawyers successfully argued that the oral vaccine, which contained a live virus, passed through the baby's system and infected him. Tenuto, who uses a wheelchair, lost his job and sued two years after contracting polio.
"When I found myself paralyzed, a co-worker of mine called the hospital," he said. "Little did I know that I would be paralyzed for the rest of my life."
Source: Daily News, NY, 21st March 2009.
Early Waning of Mumps Vaccine In Spanish Children
We evaluated the effectiveness of the Jeryl Lynn strain vaccine in a large outbreak of mumps in Navarre, Spain, 20062008. Each of the 241 cases of mumps occurring in children over 15 months of age born between 1998 and 2005 was compared with 5 controls individually matched by sex, birth date, district of residence and paediatrician. Vaccination history was obtained blindly from clinical records. Conditional logistic regression was used to obtain the matched odds ratios (ORs), and effectiveness was calculated as 1 − OR. Some 70% of cases had received one dose of measlesmumpsrubella vaccine, and 24% had received two doses. Overall vaccine effectiveness was 72% (95% CI, 3987%). Two doses were more effective (83%; 5494%) than a single dose (66%; 2585%). Among vaccinated children, risk was higher in those who had received the first dose after 36 months of age (OR = 3.1; 1.28.4) and those who had received the second dose 3 or more years before study enrolment (OR = 10.2; 1.570.7). Early waning of immunity in children after the second dose may contribute to reduced vaccine effectiveness for mumps prevention.
Source: Vaccine, Volume 27, Issue 15, 26 March 2009, Pages 2089-2093
46% of Mumps Cases Were In People Who Had TWO Doses Of MMR, Opposed To 25% of Cases In People Unvaccinated For MMR
Mumps outbreaks are affecting 15 times the number hit by the virus in the same period last year, writes Nick ODonoghue
By the second week of March, there were 981 cases of mumps notified to the Health Protection Surveillance Centre (HPSC) since the beginning of the year, with 453 cases notified in February alone the greatest number reported in any one month period since the outbreak began in 2004.
Those most affected are between the ages of 15 to 24 years (66.5 per cent), with slightly more males (54.8 per cent) than females having been reported.
Since the beginning of 2009, 16 new outbreaks have been reported in colleges/universities and other educational facilities (school, crèches).
Vaccination status was reported for 41 per cent of all cases, of whom 25 per cent were unvaccinated, 29 per cent were incompletely vaccinated, and 46 per cent reported two doses of vaccine.
Despite this they say that the reason that mumps is increasing is because people are only getting one dose of vaccine, when they just said further up the article that 46% had two doses of vaccine and only 25% had no vaccine.
Source: Irish Medical News,31 March 2009. http://www.irishmedicalnews.ie/index.php/current-issue/features/6-feature/1171-mumps-outbreaks-hit-record-high
Three Doses Of MMR Needed Because Two Don't Work
Following recent mumps outbreaks in highly vaccinated populations, researchers and public health officials are exploring the possibility that a routine third vaccine dose may be needed.
Routine two-dose programs for measles elimination using measles-mumps-rubella (MMR) vaccine were introduced in the U.S. in 1989 and in Canada in 1996/97. Many European countries have also adopted a routine two-dose schedule.
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But several countries saw sudden, unexpected mumps outbreaks among young adults who were largely covered by two MMR doses. Canada, too, had mumps outbreaks in 2007, but they occurred in mainly university-age groups who had not been eligible for the second MMR dose.
Analyses of immunity
The U.S. was particularly hard hit, racking up more than 6,500 mumps cases in 2006. Several analyses of the durability of mumps immunity followed, and were presented at the recent joint Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) and the annual meeting of the Infectious Diseases Society of America (IDSA).
Those studies suggested that waning immunity may have been one of the factors that contributed to the outbreak.
Were actively starting a project to understand the immune response to a third dose of MMR or monovalent mumps vaccine, said Dr. Jane Seward, deputy director of the division of viral diseases in the National Center for Immunization and Respiratory Diseases of the U.S. Centers for Disease Control and Prevention (CDC).
If we see outbreaks again like we did in 2006, especially on college campuses where there was a lot of transmission, we would consider offering a third dose during an outbreak, she told a news conference at the meeting.
That would be the first potential use to try to understand if a third dose is effective in controlling an outbreak. Then if we had ongoing mumps, we may be forced to look at changing policy. But our epidemiology right now doesnt dictate that.
Source: The Medical Post, 24 March 2009.
Baby Gets Polio After SIX Polio Vaccinations!
An 8-month-old Indian kid was infected with polio recently although he had been given six doses of vaccinations in the northern Indian state of Uttar Pradesh, local Hindi daily Hindustan said on Sunday.
The kid, Jagpal, has been infected in his left foot with P1 strain of polio virus, considered the most dangerous and capable of spreading very rapidly in the body, the newspaper quoted World Health Organization official Dinesh Kumar as saying.
So far, there was no report on whether the vaccine was faulty or how he could have contracted the disease even after repeated doses, said the report.
Local health authorities have decided to set up an additional health camp in Surajpur, where the case was discovered, to give emergency vaccinations for the children in the region, said the report.
Source: China View, 12th April 2009.
VAN UK'S Comment: They just said SIX vaccines didn't work and so they're organising emergency vaccines? That makes perfect sense.
4 CASES OF MUMPS - ALL WERE VACCINATED, DESPITE THIS, HEALTH AUTHORITY URGES ALL UNVACCINATED TO GET THE SHOT
City health officials are urging unvaccinated students at Northeastern University to get immunized against mumps after four students have shown signs consistent with the once-common childhood illness.
Dr. Anita Barry, director of infectious diseases at the Boston Public Health Commission, says laboratory results are not yet back to confirm whether the four have mumps. She says two of the students recently returned from Ireland, where there has been a mumps outbreak.
Barry says it is likely there will be more cases because the illness can be easily spread. She says all four students have medical records showing they received the mumps vaccine.
Source: The Associated Press, 17th April 2009.
Increasing Number Of Mumps Cases In Adults
The HSE is extending its MMR vaccine to fifth and sixth year secondary students because of an increasing number of cases of mumps in young adults.
Almost 2,000 cases have been reported since January, in comparison with 128 in the same period last year.
Mumps is an acute viral illness that causes fever, headache and painful swollen glands.
Source: The Belfast Telegraph, 20th April 2009.
Pneumonia Vaccine Has Limited Efficacy In Adults
Clinical question Is the pneumococcal polysaccharide vaccine (PPV) effective for adults?
Bottom line The evidence to support the efficacy of PPV in adults is limited at best. The best studies have not shown a consistent benefit, particularly in the most vulnerable populations that we currently target.
When all available data are combined for the outcomes of presumptive pneumonococcal pneumonia (11 studies, 56,564 participants), there was a benefit to vaccination (relative risk [RR] = 0.64; 95% CI, 0.43- 0.96). The same was true for any pneumonia (19 studies, 82,665 participants; RR = 0.73; 0.56-0.94). However, there was no benefit in terms of death from pneumonia (odds ratio [OR] = 0.88; 0.62-1.25) or all-cause mortality (OR = 0.97; 0.87-1.09).
Source: Journal of the American Academy of Physician Assistants, 21 April 2009.
Vitamin A Supplementation (VAS) Lowered Death Rate After BCG Vaccine But Increased It In Girls After DPT Vaccine
Unexpectedly, we found no overall beneficial effect on mortality in a randomised trial of vitamin A supplementation (VAS) or placebo administered with BCG vaccine at birth in Guinea-Bissau. We conducted an explorative analysis to examine whether subsequent diphtheriatetanuspertussis (DTP) vaccinations had modified the effect of VAS at birth. VAS was associated with a weak tendency for decreased mortality as long as BCG was the most recent vaccination, the mortality rate ratio being 0.86 (0.481.54); 0.82 (0.322.08) in girls and 0.89 (0.431.88) in boys. However, after DTP vaccination VAS at birth was associated with increased mortality in girls (2.19 (1.094.38)), whereas no difference was seen for boys (0.90 (0.441.82)) (p = 0.08 for equal effect of VAS in the two sexes if DTP is the last vaccine). The explanation for the lack of beneficial effect in our setting may have been that VAS at birth interacted negatively with subsequent DTP vaccinations in girls.
Source: Vaccine, Volume 27, Issue 21, 11 May 2009, Pages 2891-2898.
Polio Vaccinee's Can Excrete The Virus for YEARS and Infect Others
The live attenuated strains used in the oral poliovirus (OPV) have been the main tool in the WHO polio eradication programme. However, these strains replicate in the human gut and are excreted for several weeks after immunisation. During this period, the attenuating mutations in the vaccine strains can rapidly revert. This may, in rare cases, cause vaccine-associated paralytic poliomyelitis (VAPP) in vaccinees or result in transmissible and neurovirulent circulating vaccine-derived poliovirus (cVDPV) strains. Outbreaks of poliomyelitis caused by VDPV have recently occurred in communities with long-term incomplete immunisation coverage.
Hypogammaglobulinaemic vaccinees can chronically excrete immunodeficient VDPV (iVDPV) for several decades. As long as OPV is used, cVDPV and iVDPV pose a risk of causing poliomyelitis in unprotected individuals and threaten the goal of poliovirus eradication. VDPV cannot arise from the inactivated poliovirus vaccine (IPV), but financial and logistical barriers to replace OPV with IPV remain.
Volume 27, Issue 20, 5 May 2009, Pages 2649-2652.
VAN UK'S Comment: Notice they said 'HHypogammaglobulinaemic vaccinees can chronically excrete immunodeficient VDPV (iVDPV) for several decades'
60 Whooping Cough Cases - All Were Vaccinated Except One
More than 60 cases of whooping cough have hit Muskingum County, so many that the Zanesville Muskingum County Health Department is calling it an epidemic.
They say the illness, also known as pertussis, has hit every public school district in the county.
Medical director at the health department Vicki Whitacre says they know why it seems to be hitting more 10 and 11 year olds than any other age group.
"We know that the reasoning this is happening is because the immunizations that they receive in kindergarten are starting to wear off," said Whitacre. "All of the parents of children we've talked to have had their immunizations except one."
The article goes on to say:
Children who have been diagnosed with the illness will have their own natural immunity for four to five years.
Babies also need to get their immunizations, they aren't safe from it until their booster shot at 15 months.
Source: whiznews.com, by Audry Kensicki. 23rd April 2009.
VAN UK'S Comment: US children have 4 doses of DTaP before 18 months and another dose at 5 years, so if they're getting whooping cough at 10, that is only 'lasting' for 5 years.
When you get the natural disease, you are immune for life, not 4 to 5 years, and this was probably stated so that readers don't realise they are swapping lifelong immunity for 5 years with the vaccine.
If children aren't 'protected' till 15 months, then the vaccine is a waste of time. Whooping cough doesn't kill infants over 1 year unless they have other illnesses too, and the most dangerous time is the first 6 months of life.
60 Flu Vaccinated People Die Of Flu, And 33 Unvaccinated People
Influenza has killed 93 children under age 18 since last October, but there is no way to determine whether the current season is more severe for children than earlier years, the Centers for Disease Control and Prevention said today.
The vast majority, 33, or 73 percent, had not been vaccinated. The C.D.C. recommends that all healthy children 6 months and older be vaccinated.
Source: The New York Times, January 8th 2004.
VAN UK'S Comment: I'd like to know how they work out that the majority were unvaccinated when 93 children died, and of those 33 were unvaccinated. That means that 60 were vaccinated!