Here we report the genome of a novel rotavirus A (RVA) strain detected in a stool sample collected during routine surveillance by the Centers for Disease Control and Prevention’s New Vaccine Surveillance Network. The strain, RVA/human-wt/USA/2012741499/2012/G24P, has a genomic constellation of G24-P-I2-R2-C2-M2-A3-N2-T9-E2-H3. The VP2, VP3, VP7 and NSP3 genes cluster phylogenetically with bovine strains. The other genes occupy mixed clades containing animal and human strains. Strain RVA/human-wt/USA/2012741499/2012/G24P most likely is the product of interspecies transmission and reassortment events. This is the second report of the G24 genotype and the first report of the G24P genotype combination in humans.
Source: Infect Genet Evol. 2016 Sep;43:338-42. doi: 10.1016/j.meegid.2016.05.033. Epub 2016 May 26.
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