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MMR mass vaccination has not interrupted the circulation of rubella virus in Switzerland

n evaluating the impact of the MMR mass vaccination program begun in Switzerland in 1985, “we conclude that MMR mass vaccination has not interrupted the circulation of rubella virus in Switzerland, and that improvements in the implementation and surveillance of the MMR vaccination campaign are necessary in order to avoid [the] untoward effects of it.”

(European Journal of Epidemiology, vol. 11, no. 3, June 1995, pp. 305-10).

Increase in congenital rubella occurrence after immunisation in Greece: retrospective survey and systematic review

Abstract
Objective: To describe the events leading to the epidemic of congenital rubella syndrome in Greece in 1993 after a major rubella epidemic.

Design: Retrospective survey and systematic review.

Setting: Greece (population 10 million), 1950-95.

Subjects: Children, adolescents, and women of childbearing age.

Results: Around 1975 in Greece the measles, mumps, and rubella vaccine started being given to boys and girls aged 1 year without policies to attain high vaccination coverage and to protect adolescents and young women During the 1980s, vaccination coverage for rubella remained consistently below 50%, and the proportion of pregnant women susceptible to rubella gradually increased. In 1993 the incidence of rubella in young adults was higher than in any previous epidemic year. The epidemic of congenital rubella that followed, with 25 serologically confirmed cases (24.6 per 100 000 live births), was probably the largest such epidemic in Greece after 1950.

Conclusions: With low vaccination coverage, the immunisation of boys and girls aged 1 year against rubella carries the theoretical risk of increasing the occurrence of congenital rubella. This phenomenon, which has not been previously reported, occurred in Greece.

Source: BMJ 1999; 319 : 1462 (Published 4 December 1999)

VAN UK’s Comment: They blame low vaccination coverage but fail to mention the hundreds of reports of epidemics in almost fully vaccinated communities.

High Levels of Vaccination Induces Substantial Numbers of Symptomatic Cases (Disease) and will Lead to Larger Epidemics

Abstract

For infectious diseases where immunization can offer lifelong protection, a variety of simple models can be used to explain the utility of vaccination as a control method. However, for many diseases, immunity wanes over time and is subsequently enhanced (boosted) by asymptomatic encounters with the infection. The study of this type of epidemiological process requires a model formulation that can capture both the within-host dynamics of the pathogen and immune system as well as the associated population-level transmission dynamics. Here, we parametrize such a model for measles and show how vaccination can have a range of unexpected consequences as it reduces the natural boosting of immunity as well as reducing the number of naive susceptibles. In particular, we show that moderate waning times (40-80 years) and high levels of vaccination (greater than 70%) can induce large-scale oscillations with substantial numbers of symptomatic cases being generated at the peak. In addition, we predict that, after a long disease-free period, the introduction of infection will lead to far larger epidemics than that predicted by standard models. These results have clear implications for the long-term success of any vaccination campaign and highlight the need for a sound understanding of the immunological mechanisms of immunity and vaccination.

Source: Proc Biol Sci. 2009 Jun 7;276(1664):2071-80. Epub 2009 Mar 4.  http://www.ncbi.nlm.nih.gov/pubmed/19324753

Public Health Officials Know: Recently Vaccinated Individuals Spread Disease

Physicians and public health officials know that recently vaccinated individuals can spread disease and that contact with the immunocompromised can be especially dangerous. For example, the Johns Hopkins Patient Guide warns the immunocompromised to “Avoid contact with children who are recently vaccinated,” and to “Tell friends and family who are sick, or have recently had a live vaccine (such as chicken pox, measles, rubella, intranasal influenza, polio or smallpox) not to visit.”1

A statement on the website of St. Jude’s Hospital warns parents not to allow people to visit children undergoing cancer treatment if they have received oral polio or smallpox vaccines within four weeks, have received the nasal flu vaccine within one week, or have rashes after receiving the chickenpox vaccine or MMR (measles, mumps, rubella) vaccine.2

“The public health community is blaming unvaccinated children for the outbreak of measles at Disneyland, but the illnesses could just as easily have occurred due to contact with a recently vaccinated individual,” says Sally Fallon Morell, president of the Weston A. Price Foundation. The Foundation promotes a healthy diet, non-toxic lifestyle and freedom of medical choice for parents and their children. “Evidence indicates that recently vaccinated individuals should be quarantined in order to protect the public.”

Scientific evidence demonstrates that individuals vaccinated with live virus vaccines such as MMR (measles, mumps and rubella), rotavirus, chicken pox, shingles and influenza can shed the virus for many weeks or months afterwards and infect the vaccinated and unvaccinated alike. 3,4,5,6,7,8,9,10.11.12

Furthermore, vaccine recipients can carry diseases in the back of their throat and infect others while displaying no symptoms of a disease.13,14,15

Both unvaccinated and vaccinated individuals are at risk from exposure to those recently vaccinated. Vaccine failure is widespread; vaccine-induced immunity is not permanent and recent outbreaks of diseases such as whooping cough, mumps and measles have occurred in fully vaccinated populations.16,17 Flu vaccine recipients become more susceptible to future infection after repeated vaccination.18,19

Adults have contracted polio from recently vaccinated infants. A father from Staten Island ended up in a wheel chair after contracting polio while changing his daughter’s diaper. He received a 22.5 million dollar award in 2009. 20,21

“Vaccine failure and failure to acknowledge that live virus vaccines can spread disease have resulted in an increase in outbreaks of infectious disease in both vaccinated and unvaccinated individuals,” says Leslie Manookian, producer of The Greater Good. “CDC should instruct physicians who administer vaccinations to inform their patients about the risks posed to others by those who’ve been recently vaccinated.”

According to the Weston A. Price Foundation, the best protection against infectious disease is a healthy immune system, supported by adequate vitamin A and vitamin C. Well-nourished children easily recover from infectious disease and rarely suffer complications.

The number of measles deaths declined from 7575 in 1920 (10,000 per year in many years in the 1910s) to an average of 432 each year from 1958-1962.22 The vaccine was introduced in 1963. Between 2005 and 2014, there have been no deaths from measles in the U.S. and 108 deaths reported after the MMR vaccine.23

Source: CNBC, 3rd March 2015, http://www.cnbc.com/id/102473744#.

REFERENCES:

1. http://www.hopkinsmedicine.org/kimmel_cancer_center/patient_information/Patient%20Guide%20Final.pdf

2. http://www.stjude.org/stjude/v/index.jsp?vgnextoid=20206f9523e70110VgnVCM1000001e0215acRCRD

3. Outbreak of Measles Among Persons With Prior Evidence of Immunity, New York City, 2011 http://cid.oxfordjournals.org/content/early/2014/02/27/cid.ciu105

4. Detection of Measles Virus RNA in Urine Specimens from Vaccine Recipients http://www.ncbi.nlm.nih.gov/pubmed/7494055

5. Comparison of the Safety, Vaccine Virus Shedding and Immunogenicity of Influenza Virus Vaccine, Trivalent, Types A and B, Live Cold-Adapted, Administered to Human Immunodeficiency Virus (HIV)-Infected and Non-HIV Infected Adults http://jid.oxfordjournals.org/content/181/2/725.full

6. Sibling Transmission of Vaccine-Derived Rotavirus (RotaTeq) Associated with Rotavirus Gastroenteritis http://pediatrics.aappublications.org/content/125/2/e438

7. Polio vaccination may continue after wild virus fades http://www.cidrap.umn.edu/news-perspective/2008/10/polio-vaccination-may-continue-after-wild-virus-fades

8. Engineering attenuated virus vaccines by controlling replication fidelity http://www.nature.com/nm/journal/v14/n2/abs/nm1726.html

9. CASE OF VACCINE-ASSOCIATED MEASLES FIVE WEEKS POST-IMMUNISATION, BRITISH COLUMBIA, CANADA, OCTOBER 2013 http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20649

10. The Safety Profile of Varicella Vaccine: A 10-Year Review http://jid.oxfordjournals.org/content/197/Supplement_2/S165.full

11. Comparison of Shedding Characteristics of Seasonal Influenza Virus (Sub)Types and Influenza A(H1N1)pdm09; Germany, 2007-2011 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051653

12. Epigenetics of Host-Pathogen Interactions: The Road Ahead and the Road Behind http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003007

13. Animal Models for Influenza Virus Pathogenesis and Transmission http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063653/

14. Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate mode http://www.ncbi.nlm.nih.gov/pubmed/24277828

15. Study Finds Parents Can Pass Whooping Cough to Babies http://www.nytimes.com/2007/04/03/health/03coug.html?_r=0

16. Immunized People Getting Whooping Cough http://www.kpbs.org/news/2014/jun/12/immunized-people-getting-whooping-cough/

17. Vaccine Failure — Over 1000 Got Mumps in NY in Last Six Months http://articles.mercola.com/sites/articles/archive/2010/03/06/vaccine-failure-over-1000-get-mumps-in-ny-in-last-six-months.aspx

18. Impact of Repeated Vaccination on Vaccine Effectiveness Against Influenza A(H3N2) and B During 8 Seasons http://cid.oxfordjournals.org/content/early/2014/09/29/cid.ciu680.full

19. http://articles.mercola.com/sites/articles/archive/2012/09/18/flu-shot-increases-flu-illness.aspx

20. http://www.nydailynews.com/new-york/staten-island-dad-22-5m-polio-case-lederle-laboratories-article-1.369105

21. http://naturalsociety.com/woman-contracts-polio-virus-vaccinated-infant/

22. http://www.cdc.gov/mmwr/preview/mmwrhtml/00056803.htm

23. http://vaccineimpact.com/2015/zero-u-s-measles-deaths-in-10-years-but-over-100-measles-vaccine-deaths-reported/

 

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