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INFANRIX HEXA (Diphtheria, Tetanus, Pertussis, Hib, Polio and Hepatitis B vaccine)

Diphtheria Toxoid

Tetanus Toxoid

Pertussis Toxoid

Filamentous Haemagglutinin (FHA) – This is an adherent that helps pertussis bacterium to the host’s cells.  http://www.pnas.org/content/pnas/86/8/2637.full.pdf

Pertactin – Also an adherent and helps pertussis to attach itself to respiratory cells. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/pertactin

Three strains of polio virus – Mahoney strain, MEF-1 strain, Saukett strain).

Haemophilus influenzae type b polysaccharide (hib bacterium).

Polyribosylribitol phosphate –  This is a capsule of the hib bacterium that suppresses the activity of phagocytes. Phagocytes are cells that absorb and neutralise bacteria. https://www.merriam-webster.com/medical/polyribosylribitol%20phosphate and https://www.biology-online.org/dictionary/Phagocyte

Aluminium hydroxide.

Aluminium phosphate.

Yeast Cells.

Propagated in VERO cells – vero cells are monkey kidney tissue – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126517/

The vaccine may contain traces of formaldehyde, neomycin and polymyxin which are used during the manufacturing process. Formaldehyde is a flammable chemical that is the main component of embalming fluid. It also used in household products and vaccines. It ‘kills’ (attenuates) the viruses and bacteria in inactivated vaccines. It is a carcinogen and has been implicated in causing nasal cancer and leukaemia. https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/formaldehyde/formaldehyde-fact-sheet

List of Excipients (products used in manufacture that may be in the finished product in trace amounts):

Sodium chloride.

Medium 199 containing principally amino acids, mineral salts, vitamins.

Lactose anhydrous.

Infanrix Hexa Data Sheet:

https://www.medicines.org.uk/emc/product/2586

Prevenar 13 Vaccine for Pneumonia

Prevenar is a 13-in-1 vaccine containing:

Pneumococcal polysaccharide serotype 11 2.2 µg
Pneumococcal polysaccharide serotype 31 2.2 µg
Pneumococcal polysaccharide serotype 41 2.2 µg
Pneumococcal polysaccharide serotype 51 2.2 µg
Pneumococcal polysaccharide serotype 6A1 2.2 µg
Pneumococcal polysaccharide serotype 6B1 4.4 µg
Pneumococcal polysaccharide serotype 7F1 2.2 µg
Pneumococcal polysaccharide serotype 9V1 2.2 µg
Pneumococcal polysaccharide serotype 141 2.2 µg
Pneumococcal polysaccharide serotype 18C1 2.2 µg
Pneumococcal polysaccharide serotype 19A1 2.2 µg
Pneumococcal polysaccharide serotype 19F1 2.2 µg
Pneumococcal polysaccharide serotype 23F1 2.2 µg

Carrier Protein.

Aluminium phosphate (0.125mgs).

Excipients:

Sodium chloride

Succinic acid

Polysorbate 80 (also called tween 80 and squalene oil) – polysorbate 80 is an emulsifier that has been implicated in infertility in rats and it is used in sterilant vaccines for animals. One patent for a fertility impairing animal vaccine describes squalene oil as the perfect ingredient for sterilization. It is also used in anti-depressant medication because it carries drugs beyond the blood brain barrier to act upon the brain.  https://www.ncbi.nlm.nih.gov/pubmed/8473002/ https://patentscope.wipo.int/search/en/detail.jsf;jsessionid=D79B79962B598303993482362C10267B.wapp1nA?docId=WO1999034825&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCTDescription  https://link.springer.com/article/10.1023%2FA%3A1018983904537

Meningitis B Vaccine

Meningitis B vaccine contains:

Recombinant Neisseria meningitidis group B NHBA fusion protein.

Recombinant Neisseria meningitidis group B NadA protein.(50 mcgs each).

Outer membrane vesicles (OMV) from Neisseria meningitidis group B strain NZ98/254 (25 mcgs).

Produced in E. coli cells by recombinant DNA technology.

Aluminium hydroxide (0.5 mgs).

NHBA (Neisseria Heparin Binding Antigen), NadA (Neisserial adhesin A), fHbp (factor H binding protein).

EXCIPIENTS:

Sodium chloride

Histidine – an amino acid.

Sucrose.

BEXSERO DATA SHEET:

https://www.medicines.org.uk/emc/product/5168

Meningitis C Vaccine

Meningitis C vaccine contains:

Neisseria meningitidis group C (strain C11) polysaccharide (de-O-acetylated) (10 mcgs).

Tetanus toxoid – (10-20 mcgs).

Aluminium hydroxide (0.5 mgs).

EXCIPIENTS:

Sodium chloride.

Rotavirus Vaccine

Human rotavirus RIX4414 strain (live, attenuated).

Produced on Vero cells.

Sucrose.

EXCIPIENTS:

Sucrose

Di-sodium Adipate

Dulbecco’s Modified Eagle Medium (DMEM) – used for cell culture, contains  L-glutamine, phenol red, sodium pyruvate and sodium bicarbonate powder. https://www.sigmaaldrich.com/life-science/cell-culture/cell-culture-products.html?TablePage=14255976

ROTAVIRUS VACCINE DATA SHEET:

https://www.medicines.org.uk/emc/product/201/smpc

MMR VACCINE

MMR vaccine contains:

Measles virus1 Enders’ Edmonston strain (live, attenuated).

Mumps virus1 Jeryl Lynn™ [Level B] strain (live, attenuated).

Rubella virus2 Wistar RA 27/3 strain (live, attenuated).

Produced in chick embryo cells.

Produced in WI-38 human diploid lung fibroblasts – lung tissue from aborted human babies – https://autismoevaccini.files.wordpress.com/2016/10/walvax-2.pdf http://science.sciencemag.org/content/196/4285/60

The vaccine may contain traces of recombinant human albumin (rHA) – a human blood product.

This vaccine contains a trace amount of neomycin – an antibiotic.

he vaccine contains 14.5 mg of sorbitol.

EXCIPIENTS:

Sorbitol

Sodium phosphate

Potassium phosphate

Sucrose

Hydrolysed gelatin

Medium 199 with Hanks’ salts

Minimum Essential Medium, Eagle (MEM)

Monosodium L-glutamate

Neomycin

Phenol red

Sodium bicarbonate

Hydrochloric acid (to adjust pH)

Sodium hydroxide (to adjust pH)

Solvent 

MMR DATA SHEET:

https://www.medicines.org.uk/emc/product/6307

 

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