INFANRIX HEXA (Diphtheria, Tetanus, Pertussis, Hib, Polio and Hepatitis B vaccine)
Diphtheria Toxoid
Tetanus Toxoid
Pertussis Toxoid
Filamentous Haemagglutinin (FHA) – This is an adherent that helps pertussis bacterium to the host’s cells. http://www.pnas.org/content/pnas/86/8/2637.full.pdf
Pertactin – Also an adherent and helps pertussis to attach itself to respiratory cells. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/pertactin
Three strains of polio virus – Mahoney strain, MEF-1 strain, Saukett strain).
Haemophilus influenzae type b polysaccharide (hib bacterium).
Polyribosylribitol phosphate – This is a capsule of the hib bacterium that suppresses the activity of phagocytes. Phagocytes are cells that absorb and neutralise bacteria. https://www.merriam-webster.com/medical/polyribosylribitol%20phosphate and https://www.biology-online.org/dictionary/Phagocyte
Aluminium hydroxide.
Aluminium phosphate.
Yeast Cells.
Propagated in VERO cells – vero cells are monkey kidney tissue – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126517/
The vaccine may contain traces of formaldehyde, neomycin and polymyxin which are used during the manufacturing process. Formaldehyde is a flammable chemical that is the main component of embalming fluid. It also used in household products and vaccines. It ‘kills’ (attenuates) the viruses and bacteria in inactivated vaccines. It is a carcinogen and has been implicated in causing nasal cancer and leukaemia. https://www.cancer.gov/about-cancer/causes-prevention/risk/substances/formaldehyde/formaldehyde-fact-sheet
List of Excipients (products used in manufacture that may be in the finished product in trace amounts):
Sodium chloride.
Medium 199 containing principally amino acids, mineral salts, vitamins.
Lactose anhydrous.
Infanrix Hexa Data Sheet:
https://www.medicines.org.uk/emc/product/2586
Prevenar 13 Vaccine for Pneumonia
Prevenar is a 13-in-1 vaccine containing:
Pneumococcal polysaccharide serotype 11 | 2.2 µg |
Pneumococcal polysaccharide serotype 31 | 2.2 µg |
Pneumococcal polysaccharide serotype 41 | 2.2 µg |
Pneumococcal polysaccharide serotype 51 | 2.2 µg |
Pneumococcal polysaccharide serotype 6A1 | 2.2 µg |
Pneumococcal polysaccharide serotype 6B1 | 4.4 µg |
Pneumococcal polysaccharide serotype 7F1 | 2.2 µg |
Pneumococcal polysaccharide serotype 9V1 | 2.2 µg |
Pneumococcal polysaccharide serotype 141 | 2.2 µg |
Pneumococcal polysaccharide serotype 18C1 | 2.2 µg |
Pneumococcal polysaccharide serotype 19A1 | 2.2 µg |
Pneumococcal polysaccharide serotype 19F1 | 2.2 µg |
Pneumococcal polysaccharide serotype 23F1 | 2.2 µg |
Carrier Protein.
Aluminium phosphate (0.125mgs).
Excipients:
Sodium chloride
Succinic acid
Polysorbate 80 (also called tween 80 and squalene oil) – polysorbate 80 is an emulsifier that has been implicated in infertility in rats and it is used in sterilant vaccines for animals. One patent for a fertility impairing animal vaccine describes squalene oil as the perfect ingredient for sterilization. It is also used in anti-depressant medication because it carries drugs beyond the blood brain barrier to act upon the brain. https://www.ncbi.nlm.nih.gov/pubmed/8473002/ https://patentscope.wipo.int/search/en/detail.jsf;jsessionid=D79B79962B598303993482362C10267B.wapp1nA?docId=WO1999034825&recNum=1&maxRec=&office=&prevFilter=&sortOption=&queryString=&tab=PCTDescription https://link.springer.com/article/10.1023%2FA%3A1018983904537
Meningitis B Vaccine
Meningitis B vaccine contains:
Recombinant Neisseria meningitidis group B NHBA fusion protein.
Recombinant Neisseria meningitidis group B NadA protein.(50 mcgs each).
Outer membrane vesicles (OMV) from Neisseria meningitidis group B strain NZ98/254 (25 mcgs).
Produced in E. coli cells by recombinant DNA technology.
Aluminium hydroxide (0.5 mgs).
NHBA (Neisseria Heparin Binding Antigen), NadA (Neisserial adhesin A), fHbp (factor H binding protein).
EXCIPIENTS:
Sodium chloride
Histidine – an amino acid.
Sucrose.
BEXSERO DATA SHEET:
https://www.medicines.org.uk/emc/product/5168
Meningitis C Vaccine
Meningitis C vaccine contains:
Neisseria meningitidis group C (strain C11) polysaccharide (de-O-acetylated) (10 mcgs).
Tetanus toxoid – (10-20 mcgs).
Aluminium hydroxide (0.5 mgs).
EXCIPIENTS:
Sodium chloride.
Rotavirus Vaccine
Human rotavirus RIX4414 strain (live, attenuated).
Produced on Vero cells.
Sucrose.
EXCIPIENTS:
Sucrose
Di-sodium Adipate
Dulbecco’s Modified Eagle Medium (DMEM) – used for cell culture, contains L-glutamine, phenol red, sodium pyruvate and sodium bicarbonate powder. https://www.sigmaaldrich.com/life-science/cell-culture/cell-culture-products.html?TablePage=14255976
ROTAVIRUS VACCINE DATA SHEET:
https://www.medicines.org.uk/emc/product/201/smpc
MMR VACCINE
MMR vaccine contains:
Measles virus1 Enders’ Edmonston strain (live, attenuated).
Mumps virus1 Jeryl Lynn™ [Level B] strain (live, attenuated).
Rubella virus2 Wistar RA 27/3 strain (live, attenuated).
Produced in chick embryo cells.
Produced in WI-38 human diploid lung fibroblasts – lung tissue from aborted human babies – https://autismoevaccini.files.wordpress.com/2016/10/walvax-2.pdf http://science.sciencemag.org/content/196/4285/60
The vaccine may contain traces of recombinant human albumin (rHA) – a human blood product.
This vaccine contains a trace amount of neomycin – an antibiotic.
he vaccine contains 14.5 mg of sorbitol.
EXCIPIENTS:
Sorbitol
Sodium phosphate
Potassium phosphate
Sucrose
Hydrolysed gelatin
Medium 199 with Hanks’ salts
Minimum Essential Medium, Eagle (MEM)
Monosodium L-glutamate
Neomycin
Phenol red
Sodium bicarbonate
Hydrochloric acid (to adjust pH)
Sodium hydroxide (to adjust pH)
Solvent
MMR DATA SHEET:
https://www.medicines.org.uk/emc/product/6307
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