Human enteroviruses (EV) belong to the Picornaviridae family and are among the most common viruses infecting humans. They consist of up to 100 immunologically and genetically distinct types: polioviruses, coxsackieviruses A and B, echoviruses...Read more
Evolution and Emergence of Enteroviruses through Intra- and Inter-species Recombination: Plasticity and Phenotypic Impact of Modular Genetic Exchanges in the 5′ Untranslated Region.
Abstract Genetic recombination shapes the diversity of RNA viruses, including enteroviruses (EVs), which frequently have mosaic genomes. Pathogenic circulating vaccine-derived poliovirus (cVDPV) genomes consist of mutated vaccine poliovirus (PV)...Read more
Common and diverse features of cocirculating type 2 and 3 recombinant vaccine-derived polioviruses isolated from patients with poliomyelitis and healthy children.
Abstract BACKGROUND: Five cases of poliomyelitis due to type 2 or 3 recombinant vaccine-derived polioviruses (VDPVs) were reported in the Toliara province of Madagascar in 2005. METHODS: We sequenced the genome of the VDPVs isolated from the...Read more
Recombination between poliovirus and coxsackie A viruses of species C: a model of viral genetic plasticity and emergence.
Abstract Genetic recombination in RNA viruses was discovered many years ago for poliovirus (PV), an enterovirus of the Picornaviridae family, and studied using PV or other picornaviruses as models. Recently, recombination was shown to be a...Read more
Study found vaccine strain polio viruses in the sewerage system in Switzerland. 20 out of 174 waste water samples contained 62 isolates of polio. Three quarters of the strains found had mutated into a virulant type capable of infecting others...Read more
Characterization of four vaccine-related polioviruses including two intertypic type 3/type 2 recombinants associated with aseptic encephalitis.
Polio Virus Has Mutated! Type 2 and Type 3 Vaccine Viruses Have Recombined into a New Form of Polio. Vaccine Viruses Have also Recombined with human enterovirus C to Produce a New Polio. Abstract BACKGROUND: Four vaccine-related polioviruses...Read more
Abstract Since the World Health Assembly’s 1988 resolution to eradicate poliomyelitis, one of the main tools of the World Health Organization (WHO) Global Polio Eradication Initiative (GPEI) has been the live, attenuated oral poliovirus...Read more
A case-control study evaluating the relationship between thimerosal-containing haemophilus influenzae type b vaccine administration and the risk for a pervasive developmental disorder diagnosis in the United States.
Abstract Thimerosal is an organic mercury (Hg)-containing compound (49.55 % Hg by weight) historically added to many multi-dose vials of vaccine as a preservative. A hypothesis testing case-control study evaluated automated medical records in the...Read more
The group Moms Across America, who campaign against GMO’s, had several vaccines independently tested and found they had ‘Roundup’ pesticide in them. These vaccines were tested: MMR II (Merk) vaccine had 2.671 parts per billion...Read more
We report a 14-month-male child, who developed Hemophilus influenzae meningitis after three primary doses of the vaccine. The child presented with fever and seizures. H. influenzae was isolated from both cerebrospinal fluid (CSF) and blood. The...Read more
Click on link for NPR transcript about polio vaccine. http://www.npr.org/templates/transcript/transcript.php?storyId=474725579Read more