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Vaccines and Seizures

Extract from The Whooping Cough Immunisation Controversy

‘In the few days after pertussis immunisation a child is more likely than at other times to develop an acute neurological illness which may leave permanent neurological handicap…the recommended contraindications to pertussis immunisation are genuine and important because children immunised in spite of contraindications are more likely to suffer neurological complications….the relative risk was significantly higher in the 7 days after DTP immunisation and particularly in the first 72 hours than the control children (who had not been given pertussis vaccine)….the authors estimate that the attributable risk of a serious neurological disorder after pertussis immunisation is 1 in 110,000 (whole cell) immunisations and of lasting neurological damage the risk is 1 in 310,000. Assuming a full course of three immunisations the risk of lasting neurological damage per immunised child is about 1 in 100,000.’
Source: Archives of Disease in Childhood, 1981, 56, 577-580.

Full Text Here:g
http://adc.bmj.com/content/56/8/577.full.pdf

Etiologies for Seizures Around the Time of Vaccination

Source: Pediatrics, (doi: 10.1542/peds.2014-0690)

http://pediatrics.aappublications.org/content/early/2014/09/09/peds.2014-0690

The Risk of Seizures after Receipt of Whole-Cell Pertussis or Measles, Mumps, and Rubella Vaccine

http://www.2minutemedicine.com/majority-of-vaccine-induced-seizures-linked-to-underlying-epilepsy-syndromes/

Neuro-inflammation, blood-brain barrier, seizures and autism

Source: J Neuroinflammation. 2011; 8: 168.

Neuro-inflammation, blood-brain barrier, seizures and autism – Full Paper

This research paper was dedicated to the memory of Elias Tembenis, a little boy who died of vaccine induced epilepsy – court ruling below.

Harry Tembenis and Gina Tembenis, administrators of the estate of Elias Tembenis vs. Secretary of Health and Human Services, U.S

Febrile seizures following measles and varicella vaccines in young children in Australia.

Source: Vaccine. 2015 Mar 10;33(11):1412-7. doi: 10.1016/j.vaccine.2014.10.071. Epub 2014 Nov 7.

Febrile seizures following measles and varicella vaccines in young children in Australia.

Risk of febrile seizures after first dose of measles-mumps-rubella-varicella vaccine: a population-based cohort study

Source: CMAJ. 2014 Aug 5;186(11):824-9. doi: 10.1503/cmaj.140078. Epub 2014 Jun 9.

Risk of febrile seizures after first dose of measles-mumps-rubella-varicella vaccine: a population-based cohort study.

General practice encounters following seasonal influenza vaccination as a proxy measure of early-onset adverse events.

Source: Vaccine. 2014 Apr 17;32(19):2204-8. doi: 10.1016/j.vaccine.2014.02.044. Epub 2014 Mar 6.

General practice encounters following seasonal influenza vaccination as a proxy measure of early-onset adverse events.

Nonfebrile seizures after mumps, measles, rubella, and varicella-zoster virus combination vaccination with detection of measles virus RNA in serum, throat, and urine.

Source: Clin Vaccine Immunol. 2013 Jul; 20(7): 1094–1096.Nonfebrile Seizures after Mumps, Measles, Rubella, and Varicella-Zoster Virus Combination Vaccination with Detection of Measles Virus RNA in Serum, Throat, and Urine

A 44-year-old patient with a new-onset seizure disorder after vaccination against Japanese encephalitis: a case report.

Source: J Med Case Rep. 2013 Mar 12;7:66. doi: 10.1186/1752-1947-7-66.

A 44-year-old patient with a new-onset seizure disorder after vaccination against Japanese encephalitis: a case report.

Febrile seizures and measles-mumps-rubella-varicella (MMRV) vaccine: what do primary care physicians think?

Source: Vaccine. 2012 Nov 6;30(48):6731-3. doi: 10.1016/j.vaccine.2012.08.075. Epub 2012 Sep 10.

Febrile seizures and measles-mumps-rubella-varicella (MMRV) vaccine: what do primary care physicians think?

Febrile events including convulsions following the administration of four brands of 2010 and 2011 inactivated seasonal influenza vaccine in NZ infants and children: the importance of routine active safety surveillance.

Source: Vaccine. 2012 Jul 13;30(33):4945-52. doi: 10.1016/j.vaccine.2012.05.052. Epub 2012 Jun 1.

Febrile events including convulsions following the administration of four brands of 2010 and 2011 inactivated seasonal influenza vaccine in NZ infants and children: the importance of routine active safety surveillance.

Febrile Seizure Risk After Vaccination in Children 6 to 23 Months

Source: Pediatrics, June 2016.

http://pediatrics.aappublications.org/content/pediatrics/early/2016/06/02/peds.2016-0320.full.pdf

Common variants associated with general and MMR vaccine–related febrile seizures

Source: Nature Genetics 46,1274–1282 (2014) doi:10.1038/ng.31294

http://www.nature.com/ng/journal/v46/n12/full/ng.3129.html

Breakthrough: why MMR vaccine can give children febrile seizures

The highly debated MMR vaccine which protects against measles, mumps and rubella, can give children febrile seizures. Danish scientists have now discovered why this happens to some children.

Source: Science Nordic, 11th November 2014.

http://sciencenordic.com/breakthrough-why-mmr-vaccine-can-give-children-febrile-seizures

Vaccines Cause Early onset Epilepsy but Ever so Caring Health Chiefs want to Vaccinate Anyway

Childhood vaccines may trigger early onset of a severe form of infant epilepsy, but researchers say the disorder is ultimately caused by defective genes and lifesaving vaccines should not be withheld from these children.

The researchers said they feared the study published in the Lancet medical journal would scare parents away from getting their children vaccinated but stressed the babies in the study would likely have developed seizures within months regardless of the vaccine.

The disorder, called Dravet syndrome, generally begins with seizures around six months of age. These children have poor language and motor skills and difficulty relating to others.

Up to 80 percent of them have mutations in the SCN1A gene.

Anne McIntosh of the University of Melbourne’s Epilepsy Research Center and colleagues examined the medical records of 40 Dravet syndrome patients with the genetic mutation who had been vaccinated against whooping cough, or pertussis.

They said 30 percent of these children developed their first seizures within two days of receiving the vaccine but symptoms of their disorder were no worse than the other children who had their first seizures later on.

“In about 30 percent of people, it appears that (first seizures) came on rather quickly after the vaccination.

Source: Reuters Health, 4 May 2010.