Since the vaccination againts rotavirus is recommended by WHO in all the world and since it was already introduced in the vaccination schedule of many countries, I think safety information must be shared. In France two vaccines Rotarix ® from GSK...
Read moreTwo babies die in France after Rotavirus vaccinations
Health authorities in France are reviewing whether a common vaccine to prevent stomach illnesses should be given to babies, after it emerged this week that two newborns died following the inoculations. A report has been submitted to...
Read moreIndia to re-evaluate rotavirus vaccine
Delhi will be part of the Indian Government’s plan to study one lakh infants so as to re-evaluate the effect of its indigenous vaccine against rotavirus gastroenteritis which was released earlier this month. Also part of the study, which is...
Read moreComparison of virus shedding after lived attenuated and pentavalent reassortant rotavirus vaccine
Transmission of rotavirus vaccine or vaccine-reassortant strains to unvaccinated contacts has been reported. Therefore, it is essential to evaluate and characterize the nature of vaccine–virus shedding among rotavirus vaccine recipients. Two...
Read moreIdentification of Strains of Rotavirus Vaccine RotaTeq® in Infants with Gastroenteritis Following Routine Vaccination
Background RotaTeq was introduced into the Australian National Immunisation Program in 2007. This study identified and characterised rotavirus strains excreted by infants who presented with symptoms of gastroenteritis following recent RotaTeq...
Read moreRotavirus vaccine-derived shedding and viral reassortants
Two live, attenuated rotavirus vaccines, RotaTeq® (Merck) and Rotarix® (GlaxoSmithKline), have been used in Australia since July 2007 to prevent severe rotavirus gastroenteritis in children. Using active postvaccination monitoring, passive...
Read moreDetection of Rotateq Vaccine-Derived, Double-Reassortant Rotavirus in a 7-Year-Old Child with Acute Gastroenteritis
We describe a case of acute gastroenteritis in a schoolgirl associated with a detection of vaccine-derived, human-bovine double reassortant G1P[8] rotavirus, without any known contact with recently vaccinated infants. We propose that human-bovine...
Read moreVaccine-derived Human-bovine Double Reassortant Rotavirus in Infants With Acute Gastroenteritis
We describe 3 cases of acute gastroenteritis in healthy infants after vaccination with RotaTeq, shedding a G1P[8] human-bovine double reassortant rotavirus in stools. Such a double reassortant virus appears stable in vitro and may explain...
Read moreSymptomatic Infection and Detection of Vaccine and Vaccine-Reassortant Rotavirus Strains in 5 Children: A Case Series
Vaccine or vaccine-reassortant rotavirus strains were detected in fecal specimens from 5 of 106 (4.7%) immunocompetent children who required treatment for rotavirus gastroenteritis at a large pediatric hospital in Texas in 2009–2010. Four strains...
Read moreSibling Transmission of Vaccine-Derived Rotavirus (RotaTeq) Associated With Rotavirus Gastroenteritis
Although rotavirus vaccines are known to be shed in stools, transmission of vaccine-derived virus to unvaccinated contacts resulting in symptomatic rotavirus gastroenteritis has not been reported to our knowledge. We document here the occurrence...
Read moreTransfer of antibody via mother’s milk
Abstract Differing from humans, IgG from breast milk in many animal species (rodents, bovines, cats, ferrets, etc.) are transported across the intestinal epithelium into the neonatal circulation. This transport is located at the duodenal and...
Read moreRotavirus antibodies in the mother and her breast-fed infant
Abstract The transfer of rotavirus antibodies from 25 healthy mothers to their breast-fed infants was investigated during the period of lactation (mean, 3.9 months; range, 1-9 months). Furthermore, the destiny of these antibodies in the...
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