Abstract Rotavirus specific IgA, secretory component, and IgG were measured by enzyme linked immunosorbent assay in 20 pairs of mothers and babies to estimate antibody transfer from the mother, particularly from breast milk to neonatal faeces...
Read moreStudies were carried out during an outbreak of rotavirus type 2 infection in a neonatal nursery to determine the protective role of antibodies in cord blood and breast milk. The range, distribution, and geometric mean titres of rotavirus-specific...
Read moreBreast-feeding is a highly effective strategy for preventing morbidity and mortality in infancy. The human-milk glycans, which include oligosaccharides in their free and conjugated forms, constitute a major and an innate immunologic mechanism by...
Read moreAbstract Human Lactobacillus sp strain GG (Lactobacillus GG) administered during acute rotavirus diarrhea has been shown to promote clinical recovery. To elucidate the immune mechanisms behind such a favorable outcome, the ELISPOT (solid phase...
Read moreAbstract OBJECTIVES: Rotavirus (RV)-induced diarrhea poses a major health problem, particularly to infants. An effective measure to prevent RV infection is to consume breast milk with higher levels of protective IgA. We therefore examined whether...
Read moreThe reason why this vaccine was developed (aside from money) is because children in third world countries without access to clean water and often the prey of baby milk companies who would stop mothers breastfeeding their infants, would develop...
Read moreAs an NHS GP I’m bound to be involved in this programme, although the actual vaccinations will be carried out by the practice nurses. I’m immediately suspicious of the published costings. See: http://www.advisorybodies.doh…. We...
Read moreOur youngest son ended up in hospital with dehydration with this lovely bug when he was 3 weeks old, he contracted it from his cousin who was on his first visit from America, mum and dad didn’t bother telling us he has just been vaccinated...
Read moreInfants who receive the rotavirus vaccine, which protects against a severe diarrheal disease, may have a very small risk of developing a serious intestinal disorder called intussusception, a new study finds. In the study, researchers examined...
Read moreROTARIX has not been evaluated for carcinogenic or mutagenic potential, or for impairment of fertility. Efficacy Studies The data demonstrating the efficacy of ROTARIX in preventing rotavirus gastroenteritis come from 24,163 infants randomized in...
Read moreImmunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune response to ROTARIX. [See Warnings and Precautions...
Read moreIn clinical trials, ROTARIX was administered concomitantly with US-licensed and non-US-licensed vaccines. In a US coadministration study in 484 infants, there was no evidence of interference in the immune responses to any of the antigens when...
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