urveillance for rotavirus-associated diarrhea after implementation of rotavirus vaccination can assess vaccine effectiveness and identify disease-associated genotypes. During active vaccine postlicensure surveillance in the United States, we found a novel rotavirus genotype, G14P[24], in a stool sample from a child who had diarrhea. Unusual rotavirus strains may become more prevalent after vaccine implementation.
This surveillance has detected the emergence of G12P[8] and G9P[8] rotavirus genotypes, as well as 3 reported instances of US children infected with G8P[4] rotavirus (3–5,10). During the 2009 winter season (December 2008–June 2009) in Rochester, New York, 54 (30%) of 183 enrolled children with acute gastroenteritis had rotavirus infection. Fifty (94%) of 51 rotavirus strains were typical US strains, with G or P antigens contained in the licensed rotavirus vaccines; 3 were G8P[4] (10). One strain, however, appeared to be an unusual reassortant not previously reported in human infection. We describe this novel rotavirus genotype, G14P[24], found along with enteric adenovirus in a stool sample from a child with diarrhea.
Source: Emerg Infect Dis. 2013 Aug; 19(8): 1321–1323. 10.3201/eid1908.130470
